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22. Jan 2020

Research Training Group “ProMoAge – Protein Modification: A Key Mechanism for Ageing” (GRK 2155)

Written by

spokesperson: Prof. Dr. Andreas Simm, coordinator: Dr. Patrick Rainer Winterhalter
(funding 2016-2025)

Ageing leads to impairment of tissue homeostasis and functional decline of organs and represents a main risk factor for prevalent diseases such as cardiovascular disease and neurodegeneration in developed countries. To devise therapies aimed at improving the health state of the elderly, a detailed knowledge of molecular mechanisms leading to the impairment of organ function with increasing age is essential.

The aim of the Research Training Group (RTG) is to investigate posttranslational modifications (PTMs) of cellular proteins as key players in age progression. Scientists from the universities of Halle and Jena as well as from the Leibniz Institute of Age Research Jena combine their expertise from various fields of chemistry, biochemistry, molecular biology, cell biology, biomedicine and “omics”-based technologies to characterise PTM-mediated mechanisms of functional decline during ageing. [read more]


  • Friedrich-Schiller-Universität Jena
  • Leibniz-Institut für Altersforschung – Fritz-Lipmann-Institut (FLI)

Über Thomas Michael

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