Infrared Reflection-Absorption Spectroscopy (IRRAS)


This module addresses doctoral students in chemistry, physics, biophysics, and related fields with interest in understanding and using Infrared Reflection Absorption Spectroscopy (IRRAS). It introduces the basic theoretical and technical concepts of infrared spectroscopy in general and the specific features of IRRAS at the air/water interface. The potential of this technique as well as their applicability to polymeric systems will be discussed.


Day 1:

  • Lectures in the morning to understand the basic principle of IRRAS
  • Lab course in the afternoon to set up an IRRAS measurement

Day 2:

iRTG Program WiSe 2016/17 – Overview

Doctoral students seminars

18. October 2016 at MLU (VDP3, 1.03):

S. Pylaeva on Molecular dynamics simulations of polyQ14: structural and spectroscopic parameters (abstract)

29. November 2016 at UL

P. Leube on Characterization of the multiresponsive Poly(N,N-dimethylaminoethyl methacrylate) by spin probing EPR spectroscopy (abstract)

06. December 2016 at MLU

E. Schreck on Polymers on Surfaces – or how to catch them all (abstract)

31st January 2017 at MLU

Z. Evgrafova on Amyloid Beta Aggregation in the Presence of Temperature-Sensitive Polymers (abstract)

21st February 2017 at UL

A. Korn on Serine substitution in Amyloid-β – a possible link between β-Methylamino-L-alanine and Alzheimer’s disease? (abstract)

14th March 2017 at MLU

P. Enke on The effect of different crowding agents on structure and dynamics of unfolded proteins.

Advanced Training Modules


  • 3rd Minisymposium Leipzig – 02. December 2016
  • 4th Mini workshop – May 12, 2017

Soft skill seminars

Supplementary Study

Talk by S. Pylaeva at MLU (October 18th 2016)

Molecular dynamics simulations of polyQ14: structural and spectroscopic parameters

Polyglutamine proteins (PolyQ) are members of a big family of intrinsically disordered proteins or IDPs. Very flexible as monomers in solutions PolyQs tend to aggregate and form amyloid fibrils which were shown to be neurodegenerative. [1]

Continue reading “Talk by S. Pylaeva at MLU (October 18th 2016)”

Talk by Z. Evgrafova at MLU (January 31, 2017)

Amyloid Beta Aggregation in the Presence of Temperature-Sensitive Polymers

The formation of amyloid fibrils is considered to be one of the main causes for many neurodegenerative diseases, such as Alzheimer’s, Parkinson’s or Huntington’s disease [1]. Current knowledge suggests that amyloid-aggregation represents a nucleation-dependent aggregation process in vitro, where a sigmoidal growth phase follows an induction period. Here, we studied the fibrillation of amyloid β 1-40 (Aβ40) in the presence of thermoresponsive polymers, expected to alter the Aβ40 fibrillation kinetics due to their lower critical solution behavior [2-6]. Continue reading “Talk by Z. Evgrafova at MLU (January 31, 2017)”

Dr. Seidlitz, Anne – Experimental physics (Thurn-Albrecht, MLU)

Title of thesis: “Einfluss von Kristallisationskinetik und Dynamik im Kristall und in der Schmelze auf die Strukturbildung teilkristalliner Polymere”

Date of defence: July 14, 2016

Research topic: 
Effects of topological constraints in polymer melts on crystallization and structure formation


  • Small Angle X-ray Scattering (SAXS)
  • Polarization Microscopy
  • Rheology

Dr. Yan, Tingzi – Experimental physics (Thurn-Albrecht, MLU)

Title of thesis: “Self-assembly, rheological properties and self-healing studies of supramolecular polymers in the bulk state”

Date of defence: November 30, 2015

Research topic: 
Dynamics of self-assembled supramolecular polymers


  • Rheology
  • Small Angle X-ray Scattering (SAXS)
  • Fourier Transformed Infrared Spectroscopy (FTIR)

Dr. Mapesa, Emmanuel Urandu – Experimental physics (Kremer, UL)

Date of defence: October 30, 2014

Research topic: Molecular dynamics of polymers close to a metal interface


  • Broadband Dielectric Spectroscopy (BDS),
  • Fourier Transformed Infrared Spectroscopy (FTIR),
  • AC Calorimetry,
  • Differential Scanning Calorimetry (DSC)
  • Atomic Force Microscopy (AFM)