{"id":5556,"date":"2022-05-05T14:08:38","date_gmt":"2022-05-05T12:08:38","guid":{"rendered":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/?p=5556"},"modified":"2022-06-22T13:04:23","modified_gmt":"2022-06-22T11:04:23","slug":"doctoral-students-seminar-june-21-2022","status":"publish","type":"post","link":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/2022\/05\/doctoral-students-seminar-june-21-2022\/","title":{"rendered":"Doctoral students seminar (June 21, 2022)"},"content":{"rendered":"\n<p><strong>Molecular structure of long n-alkanes in phospholipid membranes<\/strong><br>by Anika Wurl<\/p>\n\n\n\n<p>and <br><br><strong>Dimerization of Polyglutamine chains within the PRIME20 model<\/strong><br>by Christian Lauer<\/p>\n\n\n\n<p>hybrid seminar: VSP1, room 1.02 (Halle) + zoom<br>date: June 21, 14.30<br>chair: Afiq<\/p>\n\n\n\n<!--more-->\n\n\n\n<h5>Abstracts<\/h5>\n\n\n\n<p><strong>Molecular structure of long n-alkanes in phospholipid membranes<\/strong><br>by Anika Wurl<\/p>\n\n\n\n<p>Investigating how hydrophobic molecules mix with phospholipid bilayers and how they affect membrane properties is commonplace in Biophysics. Despite of this, a molecular-level description of a membrane model as simple as a phospholipid bilayer with long linear hydrophobic chains incorporated is still missing. Here, a molecular characterization of the incorporation of two long n-alkanes \u2014 n-eicosane (C20) and n-triacontane (C30) with 20 and 30 carbons, respectively \u2014 in phosphatidylcholine (PC) bilayers is presented. In particular, this talk focusses on how MD simulations enable an atomistic-level interpretation of measured 2H NMR spectra, which are surprisingly different for C20 and C30.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Dimerization of Polyglutamine chains within the PRIME20 model<\/strong><br>by Christian Lauer<\/p>\n\n\n\n<p>The aggregation Polyglutamine extensions in proteins is associated with neurodegenerative diseases. I use advanced Monte Carlo sampling and an intermediate-resolution protein model to investigate the thermodynamics and the nucleation processes of the aggregation. I identify and characterize pseudo-phase transitions, investigate conformations in the systems and disentangle inter- vs. intra-molecular interactions.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Molecular structure of long n-alkanes in phospholipid membranesby Anika Wurl and Dimerization of Polyglutamine chains within the PRIME20 &hellip; <a href=\"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/2022\/05\/doctoral-students-seminar-june-21-2022\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Doctoral students seminar (June 21, 2022)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":4439,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"ngg_post_thumbnail":0},"categories":[284],"tags":[],"_links":{"self":[{"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/posts\/5556"}],"collection":[{"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/users\/4439"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/comments?post=5556"}],"version-history":[{"count":7,"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/posts\/5556\/revisions"}],"predecessor-version":[{"id":5671,"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/posts\/5556\/revisions\/5671"}],"wp:attachment":[{"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/media?parent=5556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/categories?post=5556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/irtgpolymers\/wp-json\/wp\/v2\/tags?post=5556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}