{"id":25,"date":"2019-04-29T11:07:32","date_gmt":"2019-04-29T09:07:32","guid":{"rendered":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/?page_id=25"},"modified":"2026-02-06T19:00:37","modified_gmt":"2026-02-06T18:00:37","slug":"publications","status":"publish","type":"page","link":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02.png\"><img loading=\"lazy\" class=\"aligncenter wp-image-374 size-thumbnail\" src=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-150x150.png 150w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-300x300.png 300w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-1024x1024.png 1024w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-768x768.png 768w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-1536x1536.png 1536w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-2048x2048.png 2048w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/a><em>Publications with an asterisk (*) are considered highly relevant to our lab projects. Publications with 2 asterisks (**) are relevant for researching SARS-CoV-2.<br \/>\n<\/em><em>Lab members are shown underlined<br \/>\n<\/em><\/p>\n<p>2026<\/p>\n<ul>\n<li>*<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0927796X26000173\" target=\"_blank\" rel=\"noopener noreferrer\">Accessing new dimensions in high-resolution materials exploration by cryo-electron microscopy<\/a>.<br \/>\n<span style=\"text-decoration: underline\">Koralli P.<\/span>, <span style=\"text-decoration: underline\">Kyrilis F.L.<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Chochos C., <strong>Kastritis P.L.*<\/strong>. <em>Mater. Sci. Eng. R Rep..<\/em> 2026 Volume 169, 101192. doi.org\/10.1016\/j.mser.2026.101192.<\/li>\n<li>*<a href=\"https:\/\/www.nature.com\/articles\/s41467-025-65861-2\" target=\"_blank\" rel=\"noopener noreferrer\">Cryo-EM structure of photosystem II supercomplex from a green microalga with extreme phototolerance.<\/a><br \/>\n<span style=\"text-decoration: underline\">Arshad R*<\/span>, <span style=\"text-decoration: underline\">Skalidis I*<\/span>, Kope\u010dn\u00fd D, Brabencov\u00e1 S, Opat\u00edkov\u00e1 M, Il\u00edk P, Posp\u00ed\u0161il P, <span style=\"text-decoration: underline\">Hamdi F<\/span>, \u0106avar Zeljkovi\u0107 S, Kope\u010dn\u00e1 M, Roudnick\u00fd P, Laz\u00e1r D, Elias E, Croce R, <strong>Kastritis PL<\/strong>, Kou\u0159il R*. <em>Nat Commun.<\/em> 2026 Jan 9;17(1):341. doi: 10.1038\/s41467-025-65861-2.<\/li>\n<li>*<a href=\"https:\/\/journals.iucr.org\/d\/issues\/2026\/01\/00\/he5693\/index.html\" target=\"_blank\" rel=\"noopener noreferrer\">Strategies for mitigating radiation damage and improving data completeness in 3D electron diffraction of protein crystals.<\/a><br \/>\nShaikhqasem A*, <span style=\"text-decoration: underline\">Hamdi F*<\/span>, Machner L, Parthier C, Breithaupt C, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, Feller SM, <strong>Kastritis PL*<\/strong>, Stubbs MT. <em>Acta Crystallogr D Struct Biol.<\/em> 2026 Jan 1;82(Pt 1):11-22. doi: 10.1107\/S2059798325011258. Epub 2026 Jan 1.<\/li>\n<li><a href=\"https:\/\/www.biorxiv.org\/content\/10.64898\/2026.01.19.700258.abstract\" target=\"_blank\" rel=\"noopener noreferrer\">Revisiting p53: Sirt1 interaction in the light of controlling p53 acetylation levels.<\/a><br \/>\nPandey V, Hause F, Iacobucci C, Ihling CH, Tueting C, Kastritis PL, Arlt C, Sinz A. 2026. <em>bioRxiv<\/em>. 2026.01.19.700258.<\/li>\n<li><a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlehtml\/2025\/ta\/d5ta06558e\" target=\"_blank\" rel=\"noopener noreferrer\">Solid-State NMR reveals mixed side-chain organization across pores in amphiphilic covalent organic frameworks<\/a><br \/>\nBassoli S, Krushelnitsky A, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <strong>Kastritis PL<\/strong>, Saalw\u00e4chter K*, Haase F*. 2026. <em>Journal of Materials Chemistry A<\/em> 14, 1647-1656<\/li>\n<\/ul>\n<p>2025<\/p>\n<ul>\n<li>*<a class=\"docsum-title\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.09.01.673474v1.abstract\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"40456694\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=2\" data-article-id=\"40456694\">Direct evidence of acid-driven protein desolvation. <\/a>\n<div class=\"docsum-citation full-citation\"><span class=\"docsum-authors full-authors\">Hamdi F, Skalidis I, Schwerin IK, Belapure J, Semchonok DA, Kyrilis FL, T\u00fcting C, M\u00fcller J, K\u00fcnze G,<b> Kastritis PL<\/b><strong>*<\/strong>.<\/span> <em>BioRxiv<\/em>, doi.org\/10.1101\/2025.09.01.673474<span class=\"docsum-journal-citation full-journal-citation\">.<\/span><\/div>\n<\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.12.23.630100v1.abstract\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"38085825\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=2\" data-article-id=\"38085825\">Mechanism of SHP2 activation by bis-Tyr-phosphorylated Gab1.<\/a><br \/>\n<span class=\"docsum-authors full-authors\">Machner L, Shaikhqasem A, Gruber T, Hamdi F, Breithaupt C, Kniest J, Wiebe F, Lewitzky M, Parthier C, Kyrilis FL, Balbach J, <strong>Kastritis PL<\/strong>, Feller SM, Stubbs MT.<\/span><br \/>\n<span class=\"docsum-journal-citation full-journal-citation\"><em>Structure, <\/em>2025 Dec 22:S0969-2126(25)00478-2.doi: 10.1016\/j.str.2025.11.018. <\/span><\/li>\n<li style=\"text-align: left\"><a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC12559229\/\" target=\"_blank\" rel=\"noopener noreferrer\">Conserved hydrophilic checkpoints tune FocA-mediated formate:H+ symport<\/a>.<br \/>\nT\u00fcting C, Janson K, Kammel M, Ihling C, Lorenz J, Kyrilis FL, Hamdi F, Erdmann C, Sinz A, Sawers RG, Kastritis PL. <em>Nat Commun.<\/em> 2025 Oct 27;16(1):9476. doi: 10.1038\/s41467-025-65159-3.<\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40957739\/\" data-ga-category=\"result_click\" data-ga-action=\"1\" data-ga-label=\"40628274\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=1\" data-article-id=\"40628274\">Form follows function &#8211; structural interplay between DCL1 and pri-miRNAs.<\/a>\n<div class=\"docsum-citation full-citation\"><span class=\"docsum-journal-citation full-journal-citation\">Scholl CR, Grosch L, <span style=\"text-decoration: underline\">Baradei J<\/span>, <strong>Kastritis PL<\/strong>, Schoeder CT, Laubinger S. <em>Trends Plant Sci.<\/em> 2025 Sep 15:S1360-1385(25)00224-9. doi: 10.1016\/j.tplants.2025.07.016. .<\/span><\/div>\n<\/li>\n<li>*<a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40628274\/\" data-ga-category=\"result_click\" data-ga-action=\"1\" data-ga-label=\"40628274\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=1\" data-article-id=\"40628274\">Self-supervised learning for generalizable particle picking in cryo-EM micrographs. <\/a>\n<div class=\"docsum-citation full-citation\"><span class=\"docsum-authors full-authors\">Zamanos A, Koromilas P, Bouritsas G, <b>Kastritis PL<\/b>, Panagakis Y.<\/span> <span class=\"docsum-journal-citation full-journal-citation\"><em>Cell Rep Methods<\/em>. 2025 Jul 21;5(7):101089. doi: 10.1016\/j.crmeth.2025.101089.<\/span><\/div>\n<\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/40456694\/\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"40456694\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=2\" data-article-id=\"40456694\">Evidence of heteroepitaxy and solid solutions in lattice matched ternary covalent organic framework systems. <\/a>\n<div class=\"docsum-citation full-citation\"><span class=\"docsum-authors full-authors\">Winter A, Lange J, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <b>Kastritis PL<\/b>, Haase F.<\/span> <span class=\"docsum-journal-citation full-journal-citation\"><em>J Am Chem Soc<\/em>. 2025 Jun 11;147(23):19702-19710. doi: 10.1021\/jacs.5c02502.<\/span><\/div>\n<\/li>\n<li><a href=\"https:\/\/chemrxiv.org\/engage\/chemrxiv\/article-details\/683432b51a8f9bdab5f3fd3c\" target=\"_blank\" rel=\"noopener noreferrer\">Solid-State NMR reveals mixed side-chain organization across pores in amphiphilic covalent organic frameworks<\/a>.\n<div class=\"docsum-citation full-citation\"><span class=\"docsum-authors full-authors\">Bassoli S, Krushelnitsky A, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <b>Kastritis PL<\/b>, Saalw\u00e4chter K, Haase F.<\/span> <em>ChemRxiv<\/em>, doi: 10.26434\/chemrxiv-2025-62tjp.<\/div>\n<\/li>\n<li><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2025.02.13.638105v1\" target=\"_blank\" rel=\"noopener noreferrer\">Structural basis of neurofibromin tetramerization and dimer-tetramer equilibrium<\/a>.\n<div class=\"docsum-citation full-citation\"><span class=\"docsum-authors full-authors\">Si S, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Lohse S, Landfester K, Lieberwirth I, <b>Kastritis PL*<\/b>, Harder A*.<\/span> <em>BioRxiv<\/em>, doi.org\/10.1101\/2025.02.13.638105<span class=\"docsum-journal-citation full-journal-citation\">.<\/span><\/div>\n<\/li>\n<\/ul>\n<p>2024<\/p>\n<ul>\n<li>*<a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.2400912121?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub++0pubmed\" target=\"_blank\" rel=\"noopener noreferrer\">Disorder-to-order active site capping regulates the rate-limiting step of the inositol pathway.<\/a><br \/>\n<span style=\"text-decoration: underline\">Tr\u00e4ger TK<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Alfes M, Hofmann T, Schmidt C, <strong>Kastritis PL*<\/strong>. <em>Proc Natl Acad Sci U S A<\/em>. 2024 Aug 20;121(34):e2400912121. doi: 10.1073\/pnas.2400912121.<\/li>\n<li>*<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0969212624003356?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">The human touch: Utilizing AlphaFold 3 to analyze structures of endogenous metabolons<\/a>.<br \/>\n<span style=\"text-decoration: underline\">Tr\u00e4ger TK<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <strong>Kastritis PL*<\/strong>. <em>Structure<\/em>. 2024 Oct 3;32(10):1555-1562. doi: 10.1016\/j.str.2024.08.018.<\/li>\n<li>*<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0959440X24000708?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\">Structural biology in cellulo: Minding the gap between conceptualization and realization<\/a>.<br \/>\n<span style=\"text-decoration: underline\">Kyrilis FL<\/span>, Low JKK, Mackay JP, <strong>Kastritis PL*<\/strong>. <em>Curr Opin Struct Biol.<\/em> 2024 Aug;87:102843. doi: 10.1016\/j.sbi.2024.102843.<\/li>\n<li><a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2024\/sc\/d4sc03461a\" target=\"_blank\" rel=\"noopener noreferrer\">Enhancing structural control in covalent organic frameworks through steric interaction-driven linker design<\/a>.<br \/>\nWinter A, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Eichh\u00f6fer A, Saalw\u00e4chter K, <strong>Kastritis PL<\/strong>, Haase F. <em>Chem Sci<\/em>. 2024 Aug 13;15(35):14449-57. doi: 10.1039\/d4sc03461a.<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s42003-024-06204-7\" target=\"_blank\" rel=\"noopener noreferrer\">Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts<\/a>.<br \/>\n<span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author\" data-delta=\"12\"><span class=\"nlm-surname\"><span style=\"text-decoration: underline\">Schmidt L<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">Semchonok DA<\/span>, Hause G, Meister A, Ihling C, Stubbs MT, Sinz A, <\/span><\/span><strong><span class=\"highwire-citation-author\" data-delta=\"12\"><span class=\"nlm-surname\">Kastritis PL*<\/span><\/span><\/strong><span class=\"highwire-citation-author\" data-delta=\"12\"><span class=\"nlm-surname\">. <\/span><\/span><\/span><em><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">Commun Biol, <\/span><\/em><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">May 10;7(1):557. <\/span><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">doi: 10.1038\/s42003-024-06204-7.<\/span><\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38190609\/\" data-ga-category=\"result_click\" data-ga-action=\"1\" data-ga-label=\"38190609\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=1\" data-article-id=\"38190609\">Protein-Rich Rafts in Hybrid Polymer\/Lipid Giant Unilamellar Vesicles. <\/a><span class=\"docsum-authors full-authors\">Otrin N, Otrin L, Bednarz C, <span style=\"text-decoration: underline\">Tr\u00e4ger TK<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <b>Kastritis PL<\/b>, Ivanov I, Sundmacher K. <\/span><span class=\"docsum-journal-citation full-journal-citation\"><em>Biomacromolecules<\/em>. 2024 Feb 12;25(2):778-791. doi: 10.1021\/acs.biomac.3c00972.<br \/>\n<\/span><\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/38085825\/\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"38085825\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=2\" data-article-id=\"38085825\">Effect of Molecular Dynamics and Internal Water Contact on the Photophysical Properties of Red pH-Sensitive Proteins. <\/a><br \/>\n<span class=\"docsum-authors full-authors\">Schmitt FJ, Mehmood AS, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Phan HT, Reisdorf J, Rieder F, Ghane Golmohamadi F, Verma R, <b>Kastritis PL<\/b>, Laufer J.<\/span><br \/>\n<span class=\"docsum-journal-citation full-journal-citation\"><em>Biochemistry<\/em>. 2024 Jan 2;63(1):82-93. doi: 10.1021\/acs.biochem.3c00444.<br \/>\n<\/span><\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2024.12.23.630100v1.abstract\" data-ga-category=\"result_click\" data-ga-action=\"2\" data-ga-label=\"38085825\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=2\" data-article-id=\"38085825\">Mechanism of SHP2 activation by bis-Tyr-phosphorylated Gab1.<\/a><br \/>\n<span class=\"docsum-authors full-authors\">Machner L, Shaikhqasem A, Gruber T, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Breithaupt C, Kniest J, Wiebe F, Lewitzky M, Parthier C, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, Balbach J, <strong>Kastritis PL<\/strong>, Feller SM, Stubbs MT.<\/span><br \/>\n<span class=\"docsum-journal-citation full-journal-citation\"><em>BioRxiv<\/em>. doi.org\/10.1101\/2024.12.23.630100.<\/span><\/li>\n<\/ul>\n<p>2023<\/p>\n<ul>\n<li><strong>*<\/strong><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37638207\/\" data-ga-category=\"result_click\" data-ga-action=\"3\" data-ga-label=\"37638207\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=3\" data-article-id=\"37638207\">Cryo-EM of a heterogeneous biochemical fraction elucidates multiple protein complexes from a multicellular thermophilic eukaryote. <\/a><span class=\"docsum-authors full-authors\"><span style=\"text-decoration: underline\"><br \/>\nSemchonok DA<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <b>Kastritis PL*.<br \/>\n<\/b><\/span><span class=\"docsum-journal-citation full-journal-citation\"><em>J Struct Biol X<\/em>. 2023 Aug 9;8:100094. doi: 10.1016\/j.yjsbx.2023.100094.<br \/>\n<\/span><\/li>\n<li><a href=\"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/pmic.202200096\" target=\"_blank\" rel=\"noopener noreferrer\">*Enabling cryo-EM density interpretation from yeast native cell extracts by proteomics data and AlphaFold structures.<\/a><br \/>\n<span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Schmidt L<\/span>, <span style=\"text-decoration: underline\">Skalidis I<\/span>, Sinz A, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Proteomics, <\/em>2023. <strong>e2200096<\/strong>. doi: 10.1002\/pmic.202200096.<\/li>\n<li><a class=\"docsum-title\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37572332\/\" data-ga-category=\"result_click\" data-ga-action=\"4\" data-ga-label=\"37572332\" data-full-article-url=\"from_term=kastritis+p+%5Bau%5D&amp;from_sort=pubdate&amp;from_size=200&amp;from_pos=4\" data-article-id=\"37572332\">The structural principles underlying molybdenum insertase complex assembly. <\/a><span class=\"docsum-authors full-authors\"><br \/>\nHassan AH, Ihling C, Iacobucci C, <b>Kastritis PL<\/b>, Sinz A, Kruse T.<br \/>\n<\/span><span class=\"docsum-journal-citation full-journal-citation\"><em>Protein Sci.<\/em> 2023 Sep;32(9):e4753. doi: 10.1002\/pro.4753.<\/span><\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/www.nature.com\/articles\/s42003-023-04885-0\" target=\"_blank\" rel=\"noopener noreferrer\">Structural analysis of an endogenous 4-megadalton succinyl-CoA-generating metabolon.<\/a><br \/>\nSkalidis I, Kyrilis FL, T\u00fcting C, Hamdi F, Tr\u00e4ger TK, Belapure J, Hause G, Fratini M, O&#8217;Reilly FJ, Heilmann I, Rappsilber J, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Commun Biol, <\/em>2023. <strong>6<\/strong>(1):552. doi: 10.1038\/s42003-023-04885-0.<\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/www.embopress.org\/doi\/full\/10.15252\/msb.202311587\" target=\"_blank\" rel=\"noopener noreferrer\">Cracking the code of cellular protein-protein interactions: Alphafold and whole-cell crosslinking to the rescue.<\/a><span style=\"text-decoration: underline\"><br \/>\nTr\u00e4ger T<\/span>, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Mol Syst Biol, <\/em>2023. <strong>19<\/strong>(4):e11587. doi: 10.15252\/msb.202311587.<\/li>\n<li><strong>*<\/strong><a class=\"gsc_oci_title_link\" href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/pro.4523\" data-clk=\"hl=el&amp;sa=T&amp;ei=3Mz4Y52XCZeAmAH6mY-ABg\">IRAA: A statistical tool for investigating a protein\u2013protein interaction interface from multiple structures<\/a>.<br \/>\n<span style=\"text-decoration: underline\">Belapure J<\/span>, <span style=\"text-decoration: underline\">Sorokina M<\/span>, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Protein Science,<\/em> 2023. <strong>32<\/strong>(1), e4523. doi: https:\/\/doi.org\/10.1002\/pro.4523<\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/pmic.202200096\" target=\"_blank\" rel=\"noopener noreferrer\">Enabling cryo-EM density interpretation from yeast native cell extracts by proteomics data and AlphaFold structures.<\/a><br \/>\n<span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Schmidt L<\/span>, <span style=\"text-decoration: underline\">Skalidis I<\/span>, Sinz A, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Proteomics, <\/em>2023. <strong>e2200096<\/strong>. doi: 10.1002\/pmic.202200096.<\/li>\n<li><a href=\"https:\/\/academic.oup.com\/jxb\/article\/74\/12\/3630\/7100059\" target=\"_blank\" rel=\"noopener noreferrer\">Novel exotic alleles of EARLY FLOWERING 3 determine plant development in barley.<\/a><br \/>\nZahn T, Zhu Z, Ritoff N, Krapf J, Junker A, Altmann T, Schmutzer T, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <strong>Kastritis PL<\/strong>, Babben S, Quint M, Pillen K, Maurer A.&nbsp;<br \/>\n<em>J Exp Bot, <\/em>2023. <strong>74<\/strong>(12):3630-3650. doi: 10.1093\/jxb\/erad127<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0021925823017842?via%3Dihub\" target=\"_blank\" rel=\"noopener noreferrer\"> Solubilization, purification, and characterization of the hexameric form of phosphatidylserine synthase from <em>Candida albicans<\/em>. <\/a><br \/>\nZhou Y, Syed JH, Semchonok DA, Wright E, Kyrilis FL, Hamdi F, <strong>Kastritis PL<\/strong>, Bruce BD, Reynolds TB.<br \/>\n<em>J Biol Chem,<\/em> 2023. <strong>299<\/strong>(6):104756. doi: 10.1016\/j.jbc.2023.104756.<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41598-023-35437-5\" target=\"_blank\" rel=\"noopener noreferrer\">Structural assessment of the full-length wild-type tumor suppressor protein p53 by mass spectrometry-guided computational modeling.<\/a><br \/>\nDi Ianni A, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Kipping M, Ihling CH, K\u00f6ppen J, Iacobucci C, Arlt C, <strong>Kastritis PL<\/strong>, Sinz A.<br \/>\n<em>Scientific Reports,<\/em> 2023<strong>. 13<\/strong>(1):8497. doi: 10.1038\/s41598-023-35437-5.<\/li>\n<li><a class=\"gsc_oci_title_link\" href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0021979722021816\" data-clk=\"hl=el&amp;sa=T&amp;ei=sc34Y_KHN9OxmAGu7J6YBw\">Encapsulation of cannabidiol in oil-in-water nanoemulsions and nanoemulsion-filled hydrogels: A structure and biological assessment study<\/a>.<br \/>\nDemisli S, Galani E, Goulielmaki M, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, Ili\u0107 T, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Crevar M, <strong>Kastritis PL<\/strong>, Pletsa V, Nallet F, Savi\u0107 S, Xenakis A, Papadimitriou V.<br \/>\n<em><span id=\"article--publisher--name\" class=\"metadata--source-title\" data-v-4bbd2d23=\"\">Journal of Colloid and Interface Science<\/span><\/em>, 2023. <strong>634<\/strong>:<span data-v-4bbd2d23=\"\">300-313 <\/span><span class=\"metadata--doi\" data-v-4bbd2d23=\"\">doi: 10.1016\/j.jcis.2022.12.036&nbsp;<\/span><\/li>\n<\/ul>\n<p>2022<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/www.cell.com\/structure\/fulltext\/S0969-2126(22)00001-6\">Cryo-EM and artificial intelligence visualize endogenous protein community members.<\/a> <span style=\"text-decoration: underline\">Skalidis, I.<\/span>, <span style=\"text-decoration: underline\">Kyrilis, F. L.<\/span>, <span style=\"text-decoration: underline\">T\u00fcting, C.<\/span>, <span style=\"text-decoration: underline\">Hamdi, F.<\/span>, Chojnowski, G., &amp; <strong>Kastritis, PL.<\/strong> <i><br \/>\nStructure<\/i>, 2022. S0969-2126(22)00001-6. https:\/\/doi.org\/10.1016\/j.str.2022.01.001<\/li>\n<li><a class=\"gsc_oci_title_link\" href=\"https:\/\/www.nature.com\/articles\/s41586-022-05370-0\" data-clk=\"hl=el&amp;sa=T&amp;ei=68r4Y_SHGs6kmAGxoaTACA\">Cryo-EM structure of the SEA complex<\/a>.<br \/>\nTafur L, Hinterndorfer K, Gabus C, Lamanna C, Bergmann A, Sadian Y, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <strong>Kastritis PL<\/strong>, Loewith R.<br \/>\n<i>Nature,<\/i> 2022. <b>611<\/b>, 399\u2013404. https:\/\/doi.org\/10.1038\/s41586-022-05370-0<\/li>\n<li>*<a class=\"gsc_oci_title_link\" href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/acs.biomac.2c00935\" data-clk=\"hl=el&amp;sa=T&amp;ei=7Mr4Y7q2PJeAmAH6mY-ABg\">Cryo-electron microscopy snapshots of eukaryotic membrane proteins in native lipid-bilayer nanodiscs<\/a>.\n<div><span style=\"text-decoration: underline\">Janson K<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Alfes M, Das M, <span style=\"text-decoration: underline\">Tr\u00e4ger TK<\/span>, Schmidt C, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Vargas C, Keller S, <span style=\"text-decoration: underline\">Meister A<\/span>, <strong>Kastritis PL<\/strong>.<br \/>\n<cite>Biomacromolecules,<\/cite> 2022 <strong><em>23<\/em><\/strong>(12), 5084-5094 DOI: 10.1021\/acs.biomac.2c00935<\/div>\n<\/li>\n<li>*<a class=\"gsc_oci_title_link\" href=\"https:\/\/www.liebertpub.com\/doi\/full\/10.1089\/gen.42.09.22\" data-clk=\"hl=el&amp;sa=T&amp;ei=6cr4Y93GMdOxmAGu7J6YBw\">An integrative approach to probing transient protein structures in cell extracts<\/a>.\n<div class=\"art_authors\"><strong>Kastritis PL<\/strong>.<br \/>\n<span class=\"journalName\"><em>Genetic Engineering &amp; Biotechnology News<\/em><\/span>, <span class=\"year\">2022<\/span>. <strong><span class=\"volume\">42<\/span><\/strong>:<span class=\"issue\">9<\/span>, <span class=\"page\">68-70 <\/span><\/div>\n<\/li>\n<li>\n<div class=\"highwire-cite-title\">\n<div class=\"highwire-cite-title\">*<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.07.15.498668v1\">Delineating organizational principles of the endogenous L-A virus by cryo-EM and computational analysis of native cell extracts.<\/a><\/div>\n<\/div>\n<div class=\"highwire-cite-authors\"><span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author\" data-delta=\"12\"><span class=\"nlm-surname\"><span style=\"text-decoration: underline\">Schmidt L<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">Semchonok DA<\/span>, Hause G, <span style=\"text-decoration: underline\">Meister A<\/span>, Ihling C, Shah PNM, Stubbs MT, Sinz A, Stuart DI, <\/span><\/span><strong><span class=\"highwire-citation-author\" data-delta=\"12\"><span class=\"nlm-surname\">Kastritis PL <\/span><\/span><\/strong><span class=\"highwire-citation-author\" data-delta=\"12\"><span class=\"nlm-surname\">.<\/span><\/span><\/span><\/div>\n<div class=\"highwire-cite-metadata\"><em><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">bioRxiv, <\/span><\/em><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\">2022. <\/span><span class=\"highwire-cite-metadata-pages highwire-cite-metadata\">2022.07.15.498668; <\/span><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"doi_label\">doi:<\/span> https:\/\/doi.org\/10.1101\/2022.07.15.498668 <\/span><\/div>\n<\/li>\n<li><a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.langmuir.2c00872\">Filling the Gap with Long n-Alkanes: Incorporation of C20 and C30 into Phospholipid Membranes.<\/a><br \/>\nWurl&nbsp; A, Ott M, Plato E, <span style=\"text-decoration: underline\">Meister A<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <strong>Kastritis PL<\/strong>, Blume A, Ferreira TM\/<br \/>\n<em>Langmuir,<\/em> 2022. https:\/\/doi.org\/10.1021\/acs.langmuir.2c00872<\/li>\n<li>**<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283622002170\">An Electrostatically-steered Conformational Selection Mechanism Promotes SARS-CoV-2 Spike Protein Variation. <\/a><br \/>\n<span style=\"text-decoration: underline\">Sorokina M<\/span>, <span style=\"text-decoration: underline\">Belapure J<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Paschke R, Papasotiriou I, Rodrigues JPGLM, <strong>Kastritis PL<\/strong>.<br \/>\n<em>J Mol Biol<\/em><em>, <\/em>2022. https:\/\/doi.org\/10.1016\/j.jmb.2022.167637<\/li>\n<li><a href=\"https:\/\/www.pnas.org\/doi\/abs\/10.1073\/pnas.2122468119\">Increased efficiency of charge-mediated fusion in polymer\/lipid hybrid membranes. <\/a><br \/>\nMaru\u0161i\u010d N, Otrin L, Rauchhaus J, Zhao Z, <span style=\"text-decoration: underline\">Kyrilis FL.<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <strong>Kastritis PL<\/strong>, Dimova R, Ivanov I, Sundmacher K.<br \/>\n<em>Proc Natl Acad Sci U S A, <\/em>2022. https:\/\/doi.org\/10.1073\/pnas.2122468119<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0927776522000522\">Investigating bolalipids as solubilizing agents for poorly soluble drugs: Effects of alkyl chain length on solubilization and cytotoxicity.<\/a><br \/>\nLi F, Harvey RD, <span style=\"text-decoration: underline\">Modicano P<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, M\u00fcller S, Gruhle K, <strong>Kastritis PL<\/strong>, Drescher S, Dailey LA.<br \/>\n<em>Colloids and Surfaces B: Biointerfaces, <\/em>2022. https:\/\/doi.org\/10.1016\/j.colsurfb.2022.112369<\/li>\n<li>*<a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2590346221001541\">Cryo-EM structure of a tetrameric photosystem I from Chroococcidiopsis TS-821, a thermophilic, unicellular, non-heterocyst-forming cyanobacterium.<\/a><br \/>\n<span style=\"text-decoration: underline\">Semchonok DA<\/span>, Mondal J, Cooper CJ, Schlum K, Li M, Amin M, Sorzano COS, Ram\u00edrez-Aportela E, <strong>Kastritis PL<\/strong>, Boekema EJ, Guskov A, Bruce BD.<br \/>\n<em>Plant Communications, <\/em>2022. https:\/\/doi.org\/10.1016\/j.xplc.2021.100248<\/li>\n<li><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2022.06.02.493408v1.abstract\">Osmotic stress response in BetP: How lipids and K<sup>+<\/sup> team up to overcome downregulation<\/a><br \/>\n<span class=\"highwire-citation-authors\"><span class=\"highwire-citation-author\" data-delta=\"13\"><span class=\"nlm-surname\"> Heinz V, G\u00fcler G, Leone V, Madej MG, Maksimov S, G\u00e4rtner RM, Rudi O, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <strong>Kastritis PL<\/strong>, M\u00e4ntele W, Kr\u00e4mer R, Forrest LR, Perez C, Ziegler C <\/span><\/span><\/span><span class=\"highwire-cite-metadata-journal highwire-cite-metadata\"><em>bioRxiv, <\/em>2022. <\/span><span class=\"highwire-cite-metadata-pages highwire-cite-metadata\">2022.06.02.493408; <\/span><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\"><span class=\"doi_label\">doi:<\/span> https:\/\/doi.org\/10.1101\/2022.06.02.493408 <\/span><\/li>\n<\/ul>\n<p>2021<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/www.nature.com\/articles\/s41467-021-27287-4\">Cryo-EM snapshots of a native lysate provide structural insights into a metabolon-embedded transacetylase reaction.<\/a><br \/>\n<span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">M\u00fcller J<\/span>, <span style=\"text-decoration: underline\">Sorokina M<\/span>, <span style=\"text-decoration: underline\">Skalidis I<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Sadian Y, <strong>Kastritis PL<\/strong>*.<br \/>\n<em>Nature Communications<\/em>, 2021. <strong>12<\/strong>(1): 6933. <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-27287-4\">https:\/\/doi.org\/10.1038\/s41467-021-27287-4<\/a><\/li>\n<li><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.1c00714\">Nanoscale Model System for the Human Myelin Sheath<\/a>.<br \/>\nHoffmann M, Haselberger D, Hofmann T, M\u00fcller L, <span style=\"text-decoration: underline\">Janson K<\/span>, <span style=\"text-decoration: underline\">Meister A<\/span>, Das M, Vargas C, Keller S, <strong>Kastritis PL<\/strong>, Schmidt C, &amp; Hinderberger D. <i><br \/>\nBiomacromolecules<\/i>, 2021. <strong>22<\/strong>(9), 3901\u20133912. <a href=\"https:\/\/doi.org\/10.1021\/acs.biomac.1c00714\">https:\/\/doi.org\/10.1021\/acs.biomac.1c00714<\/a><\/li>\n<li><a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.chemrev.1c00786\">Cross-Linking Mass Spectrometry for Investigating Protein Conformations and Protein\u2013Protein Interactions\u2500A Method for All Seasons.<\/a><br \/>\nPiersimoni L, <strong>Kastritis PL<\/strong>, Arlt C. &amp; Sinz A.<br \/>\n<em>Chemical Reviews, <\/em>2021. <a href=\"https:\/\/doi.org\/10.1021\/acs.chemrev.1c00786\">https:\/\/doi.org\/10.1021\/acs.chemrev.1c00786<\/a><\/li>\n<li><a href=\"https:\/\/ar.iiarjournals.org\/content\/41\/6\/2953\"><i>BRCA1-BRCT<\/i> Mutations Alter the Subcellular Localization of BRCA1 <i>In Vitro<\/i>.<\/a><br \/>\nDrikos I, Boutou E, <strong>Kastritis P L<\/strong>, &amp; Vorgias CE.<br \/>\n<i>Anticancer research<\/i>, 2021. <strong>41<\/strong>(6), 2953\u20132962. <a href=\"https:\/\/doi.org\/10.21873\/anticanres.15077\">https:\/\/doi.org\/10.21873\/anticanres.15077<\/a><\/li>\n<li><a class=\"issue-item__title \" href=\"https:\/\/chemistry-europe.onlinelibrary.wiley.com\/doi\/abs\/10.1002\/anse.202100029\">Thin-Layer Chromatography and Coomassie Staining of Phospholipids for Fast and Simple Lipidomics Sample Preparation.<\/a><br \/>\nHofmann T, Barth M, <span style=\"text-decoration: underline\">Meister A<\/span>, <strong>Kastritis PL<\/strong>, Schmidt C.<br \/>\n<i>Analysis &amp; Sensing,<\/i> 2021, <strong>1<\/strong><i>:<\/i>171. <a href=\"https:\/\/doi.org\/10.1002\/anse.202100029\">https:\/\/doi.org\/10.1002\/anse.202100029<\/a><\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41467-021-25294-z\">En route to dynamic life processes by SNARE-mediated fusion of polymer and hybrid membranes.<\/a><br \/>\nOtrin L, Witkowska A, Maru\u0161i\u010d N, Zhao Z, Lira RB, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, Ivanov I, Lipowsky R, <strong>Kastritis PL<\/strong>, Dimova R, Sundmacher K, Jahn R, Vidakovi\u0107-Koch T .<br \/>\n<em>Nature Communications, <\/em>2021. <strong>12<\/strong>(1): 4972. <a href=\"https:\/\/doi.org\/10.1038\/s41467-021-25294-z\">https:\/\/doi.org\/10.1038\/s41467-021-25294-z<\/a><\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0005273621001735\">Solubilization of artificial mitochondrial membranes by amphiphilic copolymers of different charge.<\/a><br \/>\n<span style=\"text-decoration: underline\">Janson K<\/span>, Zierath J, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Semchonok DA<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">Skalidis I<\/span>, Kopf AH, Das M, Kolar C, Rasche M, Vargas C, Keller S, <strong>Kastritis PL<\/strong>*, <span style=\"text-decoration: underline\">Meister A.<\/span><br \/>\n<em>Biochim Biophys Acta Biomembr<\/em>, 2021. <strong>1863<\/strong>(12): 183725. <a href=\"https:\/\/doi.org\/10.1016\/j.bbamem.2021.183725\">https:\/\/doi.org\/10.1016\/j.bbamem.2021.183725<\/a><\/li>\n<li><strong>*<\/strong><a title=\"Back to original article\" href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0254429\">Coupling proteomics and metabolomics for the unsupervised identification of protein\u2013metabolite interactions in <i>Chaetomium thermophilum<\/i> <\/a><br \/>\nLi&nbsp;Y, Kuhn&nbsp;M, Zukowska-Kasprzyk&nbsp;J, Hennrich&nbsp;ML, <strong>Kastritis&nbsp;PL<\/strong>, et al.<br \/>\n<em>PLOS ONE<\/em>, 2021. <strong>16<\/strong>(7): e0254429. <a href=\"https:\/\/doi.org\/10.1371\/journal.pone.0254429\">https:\/\/doi.org\/10.1371\/journal.pone.0254429<\/a><\/li>\n<li><strong>***<\/strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2211124721000401\" target=\"_blank\" rel=\"noopener noreferrer\">Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts.<\/a><br \/>\n<span style=\"text-decoration: underline\">Kyrilis FL#<\/span>, <span style=\"text-decoration: underline\">Semchonok DA#<\/span>, <span style=\"text-decoration: underline\">Skalidis I<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, O&#8217;Reilly FJ, Rappsilber J, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Cell Rep., <\/em>2021. <strong>34<\/strong>(6):108727. doi: 10.1016\/j.celrep.2021.108727.<\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmolb.2021.660542\/\" target=\"_blank\" rel=\"noopener noreferrer\">Detecting Protein Communities in Native Cell Extracts by Machine Learning: A Structural Biologist\u2019s Perspective.<\/a><br \/>\n<span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Belapure J<\/span>, <strong>Kastritis PL*<\/strong><br \/>\n<em>Front Mol Biosci.<\/em> 2021. <strong>8<\/strong>:229. doi: 10.3389\/fmolb.2021.660542.<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283621001480\" target=\"_blank\" rel=\"noopener noreferrer\">First 3D-Structural Data of Full-length Guanylyl Cyclase 1 in Rod-Outer-Segment Preparations of Bovine Retina by Cross-linking\/Mass Spectrometry.<\/a><br \/>\nRehkamp A, T\u00e4nzler D, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <strong>Kastritis PL<\/strong>, Iacobucci C, Ihling CH, Kipping M, Koch KW, Sinz A*.<br \/>\n<em>J Mol Biol.<\/em> 2021. <strong>433<\/strong>(10):166947. doi: 10.1016\/j.jmb.2021.166947<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S1047847720302689\" target=\"_blank\" rel=\"noopener noreferrer\">Algorithmic robustness to preferred orientations in Single Particle Analysis by CryoEM.<\/a><br \/>\nSorzano COS, <span style=\"text-decoration: underline\">Semchonok D<\/span>, Lin SC, Lo YC, Vilas JL, Jim\u00e9nez-Moreno A, Gragera M, Vacca S, Maluenda D, Mart\u00ednez M, Ram\u00edrez-Aportela E, Melero R, Cuervo A, Conesa JJ, Conesa P, Losana P, Ca\u00f1o LD, de la Morena JJ, Fonseca YC, S\u00e1nchez-Garc\u00eda R, Strelak D, Fern\u00e1ndez-Gim\u00e9nez E, de Isidro F, Herreros D, <strong>Kastritis PL<\/strong>, Marabini R, Bruce BD, Carazo JM*.<br \/>\n<em>J Struct Biol<\/em>. 2021. <strong>213<\/strong>(1):107695. doi: 10.1016\/j.jsb.2020.107695.<\/li>\n<\/ul>\n<p>2020<\/p>\n<ul>\n<li><strong>*<\/strong><strong>*<\/strong><a href=\"https:\/\/www.nature.com\/articles\/s41597-020-00652-6\" target=\"_blank\" rel=\"noopener noreferrer\">Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.<\/a><br \/>\n<span style=\"text-decoration: underline\">Sorokina M<\/span>, M C Teixeira J, Barrera-Vilarmau S, Paschke R, Papasotiriou I, Rodrigues JPGLM, <strong>Kastritis PL*<\/strong><br \/>\n<em>Scientific Data. <\/em>2020. <strong>7<\/strong>(1):309. doi: 10.1038\/s41597-020-00652-6.<\/li>\n<li><a href=\"http:\/\/10.21203\/rs.3.rs-81702\/v1\" target=\"_blank\" rel=\"noopener noreferrer\">Cryo-EM Structure of a Tetrameric Photosystem I from Chroococcidiopsis TS-821, a Thermophilic, Non-heterocyst-forming Cyanobacteria.<\/a><br \/>\n<span style=\"text-decoration: underline\">Semchonok D<\/span>#, Mondal J#, Cooper C, Schlum K, Li M, Amin M, Sorzano CS, Ram\u00edrez-Aportela E, <strong>Kastritis PL<\/strong>, Boekema E, Guskov A, Bruce B*<br \/>\n[preprint @<a href=\"http:\/\/10.21203\/rs.3.rs-81702\/v1\" target=\"_blank\" rel=\"noopener noreferrer\"><em>Research Square<\/em> doi: 10.21203\/rs.3.rs-81702\/v1 PPR: PPR227494<\/a>]<\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/www.pnas.org\/content\/early\/2020\/08\/25\/2005301117\" target=\"_blank\" rel=\"noopener noreferrer\">Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress.<\/a><br \/>\nZhou Y#, <strong>Kastritis PL#*<\/strong>, Dougherty SE, Bouvette J, Hsu AL, Burbaum L, Mosalaganti S, Pfeffer S, Hagen W, F\u00f6rster F, Borgnia MJ, Vogel C, Beck M, Bartesaghi A*, Silva GM*<br \/>\n<em>Proc Natl Acad Sci U S A.<\/em> 2020. Aug 27:202005301. doi: 10.1073\/pnas.2005301117<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0939641120302204\" target=\"_blank\" rel=\"noopener noreferrer\">Enhanced optical imaging properties of lipid nanocapsules as vehicles for fluorescent conjugated polymers.<\/a><br \/>\n<span style=\"text-decoration: underline\">Modicano P<\/span>, Neumann R, Sch\u00fcller M, Holthof J, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <strong>Kastritis PL<\/strong>, M\u00e4der K, Dailey LA*<br \/>\n<em>Eur J Pharm Biopharm.&nbsp;<\/em>2020 Sep;154:297-308. doi: 10.1016\/j.ejpb.2020.07.017.<\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/biosignaling.biomedcentral.com\/articles\/10.1186\/s12964-020-00631-9\" target=\"_blank\" rel=\"noopener noreferrer\">Unstructured regions of large enzymatic complexes control the availability of metabolites with signaling functions.<\/a><br \/>\n<span style=\"text-decoration: underline\">Skalidis I,<\/span> <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <strong>Kastritis PL*<\/strong><br \/>\n<em>Cell Commun. Signal<\/em>. 2020. Aug 26;18(1):136. doi: 10.1186\/s12964-020-00631-9.<\/li>\n<li>*<a href=\"https:\/\/www.nature.com\/articles\/s41598-020-69313-3\" target=\"_blank\" rel=\"noopener noreferrer\">Structural analysis of 70S ribosomes by cross-Linking\/mass Spectrometry reveals conformational plasticity.<\/a><br \/>\n<span style=\"text-decoration: underline\">T\u00fcting C<\/span>, Iacobucci C, Ihling CE, <strong>Kastritis PL*<\/strong>, Sinz A*<br \/>\n<em>Sci<\/em> <em>Rep<\/em>. 2020. Jul 28;10(1):12618. doi: 10.1038\/s41598-020-69313-3.<\/li>\n<li><a href=\"https:\/\/www.pnas.org\/content\/early\/2020\/06\/16\/1919306117\" target=\"_blank\" rel=\"noopener noreferrer\">Constructing artificial respiratory chain in polymer compartments: Insights into the interplay between bo3 oxidase and the membrane.<\/a><br \/>\nMaru\u0161i\u010d N, Otrin L, Zhao Z, Lira RB, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Hamdi F<\/span>, <strong>Kastritis PL<\/strong>, Vidakovi\u0107-Koch T, Ivanov I, Sundmacher K, Dimova R.<br \/>\n<em>Proc Natl Acad Sci U S A.<\/em> 2020 <strong>117<\/strong>(26):15006-15017. doi: 10.1073\/pnas.1919306117<\/li>\n<li><strong>*<\/strong><strong>*<\/strong><a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.06.05.136861v1\" target=\"_blank\" rel=\"noopener noreferrer\">Insights on cross-species transmission of SARS-CoV-2 from structural modeling.<\/a><br \/>\nRodrigues PGLM J*, Barrera-Vilarmau S, Texeira MC J, Seckel E, <strong>Kastritis PL<\/strong>, Levitt M.<br \/>\n<em>PLoS computational biology <\/em>2020. <strong>16<\/strong>(12), e1008449<br \/>\n[preprint was @<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/2020.06.05.136861v2\" target=\"_blank\" rel=\"noopener noreferrer\">BioRxiv 2020 2020.06.05.136861. doi: <\/a><span class=\"highwire-cite-metadata-doi highwire-cite-metadata\">10.1101\/2020.06.05.136861]<\/span><\/li>\n<li><strong>*<\/strong><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0232540\" target=\"_blank\" rel=\"noopener noreferrer\">2.7 \u00c5 cryo-EM structure of vitrified M. musculus H-chain apoferritin from a compact 200 keV cryo-microscope.<\/a><br \/>\n<span style=\"text-decoration: underline\">Hamdi F<\/span>, <span style=\"text-decoration: underline\">T\u00fcting C<\/span>, <span style=\"text-decoration: underline\">Semchonok DA<\/span>, <span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Meister A<\/span>, <span style=\"text-decoration: underline\">Skalidis I<\/span>, <span style=\"text-decoration: underline\">Schmidt L<\/span>, Parthier C, Stubbs MT*, <strong>Kastritis PL*<\/strong><br \/>\n<em>PLOS One<\/em>. 2020. <strong>15<\/strong>(5): e0232540.<br \/>\n[preprint was @<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/738724v1\" target=\"_blank\" rel=\"noopener noreferrer\">BioRxiv 2019 738724. doi: 10.1101\/738724<\/a>]<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41467-020-16147-2\" target=\"_blank\" rel=\"noopener noreferrer\">Flexibility of intrinsically disordered degrons in AUX\/IAA proteins reinforces auxin co-receptor assemblies.<\/a><br \/>\nNiemeyer M, Castillo EM, Ihling CH, Iacobucci C, Wilde V, Hellmuth A, Hoehenwarter W, Samodelov SL, Zurbriggen MD, <strong>Kastritis PL<\/strong>, Sinz A &amp; Villalobos LIAC.<br \/>\n<em>Nature Communications<\/em>. 2020. <strong>11<\/strong>, 2277.<br \/>\n[preprint was @<a href=\"https:\/\/www.biorxiv.org\/content\/10.1101\/787770v2\" target=\"_blank\" rel=\"noopener noreferrer\">BioRxiv 2019 787770. doi: 10.1101\/787770<\/a>]<\/li>\n<\/ul>\n<p>2019<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/www.degruyter.com\/doi\/10.1515\/hsz-2018-0445\" target=\"_blank\" rel=\"noopener noreferrer\">Integrative biology of native cell extracts: a new era for structural characterization of life processes.<\/a><br \/>\n<span style=\"text-decoration: underline\">Kyrilis FL<\/span>, <span style=\"text-decoration: underline\">Meister A<\/span>, <strong>Kastritis PL*<\/strong>.<br \/>\n<em>Biol Chem<\/em>. 2019 Jun 26;400(7):831-846. doi: 10.1515\/hsz-2018-0445.<\/li>\n<li><a href=\"https:\/\/www.annualreviews.org\/doi\/abs\/10.1146\/annurev-biophys-052118-115308\" target=\"_blank\" rel=\"noopener noreferrer\">Structure and Assembly of the Nuclear Pore Complex.<\/a><br \/>\nHampoelz B, Andres-Pons A, <strong>Kastritis PL<\/strong>, Beck M.<br \/>\n<em>Annu Rev Biophys<\/em>. 2019 Apr 3. doi: 10.1146\/annurev-biophys-052118-115308.<\/li>\n<\/ul>\n<p>2018<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"http:\/\/essays.biochemistry.org\/content\/62\/4\/501.long\" target=\"_blank\" rel=\"noopener noreferrer\">Enzymatic complexes across scales.<\/a><br \/>\n<strong>Kastritis PL,<\/strong> Gavin AC.<br \/>\n<em>Essays Biochem<\/em>. 2018 Oct 26;62(4):501-514. doi: 10.1042\/EBC20180008. Print 2018 Oct 26.<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/s41596-018-0017-6\" target=\"_blank\" rel=\"noopener noreferrer\">Defining distance restraints in HADDOCK.<\/a><br \/>\nBonvin AM, Karaca E, <strong>Kastritis PL<\/strong>, Rodrigues JP.<br \/>\n<em>Nat Protoc<\/em>. 2018 Jul;13(7):1503. doi: 10.1038\/s41596-018-0017-6. Epub 2018 Jun 25. No abstract available.<\/li>\n<\/ul>\n<p>2017<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"http:\/\/msb.embopress.org\/content\/13\/7\/936.long\" target=\"_blank\" rel=\"noopener noreferrer\">Capturing protein communities by structural proteomics in a thermophilic eukaryote.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, O&#8217;Reilly FJ, Bock T, Li Y, Rogon MZ, Buczak K, Romanov N, Betts MJ, Bui KH, Hagen WJ, Hennrich ML, Mackmull MT, Rappsilber J, Russell RB, Bork P, Beck M, Gavin AC.<br \/>\n<em>Mol Syst Biol<\/em>. 2017 Jul 25;13(7):936. doi: 10.15252\/msb.20167412.<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/ncomms15035\" target=\"_blank\" rel=\"noopener noreferrer\">Subnanometre-resolution structure of the doublet microtubule reveals new classes of microtubule-associated proteins.<\/a><br \/>\nIchikawa M, Liu D, <strong>Kastritis PL<\/strong>, Basu K, Hsu TC, Yang S, Bui KH.<br \/>\n<em>Nature Communications<\/em>. 2017 May 2;8:15035. doi: 10.1038\/ncomms15035.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.25198\" target=\"_blank\" rel=\"noopener noreferrer\">Sense and simplicity in HADDOCK scoring: Lessons from CASP-CAPRI round 1.<\/a><br \/>\nVangone A, Rodrigues JP, Xue LC, van Zundert GC, Geng C, Kurkcuoglu Z, Nellen M, Narasimhan S, Karaca E, van Dijk M, Melquiond AS, Visscher KM, Trellet M, <strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>Proteins<\/em>. 2017 Mar;85(3):417-423. doi: 10.1002\/prot.25198. Epub 2016 Nov 24. Erratum in: <em>Proteins<\/em>. 2017 Aug;85(8):1589-1590.<\/li>\n<\/ul>\n<p>2016<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022-2836(15)00537-9\" target=\"_blank\" rel=\"noopener noreferrer\">The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes.<\/a><br \/>\nvan Zundert GCP, Rodrigues JP, Trellet M, Schmitz C, <strong>Kastritis PL<\/strong>, Karaca E, Melquiond ASJ, van Dijk M, de Vries SJ, Bonvin AM.<br \/>\n<em>J Mol Biol<\/em>. 2016 Feb 22;428(4):720-725. doi: 10.1016\/j.jmb.2015.09.014. Epub 2015 Sep 26.<\/li>\n<li><a href=\"https:\/\/www.frontiersin.org\/articles\/10.3389\/fmolb.2016.00046\/full\" target=\"_blank\" rel=\"noopener noreferrer\">dMM-PBSA: A New HADDOCK Scoring Function for Protein-Peptide Docking.<\/a><br \/>\nSpiliotopoulos D, <strong>Kastritis PL<\/strong>, Melquiond AS, Bonvin AM, Musco G, Rocchia W, Spitaleri A.<br \/>\n<em>Front Mol Biosci<\/em>. 2016 Aug 31;3:46. doi: 10.3389\/fmolb.2016.00046. eCollection 2016.<\/li>\n<li><a href=\"https:\/\/academic.oup.com\/bioinformatics\/article\/32\/23\/3676\/2525629\" target=\"_blank\" rel=\"noopener noreferrer\">PRODIGY: a web server for predicting the binding affinity of protein-protein complexes.<\/a><br \/>\nXue LC, Rodrigues JP, <strong>Kastritis PL<\/strong>, Bonvin AM, Vangone A.<br \/>\n<em>Bioinformatics<\/em>. 2016 Dec 1;32(23):3676-3678. Epub 2016 Aug 8.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.25007\" target=\"_blank\" rel=\"noopener noreferrer\">Prediction of homoprotein and heteroprotein complexes by protein docking and template-based modeling: A CASP-CAPRI experiment.<\/a><br \/>\nLensink MF, Velankar S, Kryshtafovych A, Huang SY, Schneidman-Duhovny D, Sali A, Segura J, Fernandez-Fuentes N, Viswanath S, Elber R, Grudinin S, Popov P, Neveu E, Lee H, Baek M, Park S, Heo L, Rie Lee G, Seok C, Qin S, Zhou HX, Ritchie DW, Maigret B, Devignes MD, Ghoorah A, Torchala M, Chaleil RA, Bates PA, Ben-Zeev E, Eisenstein M, Negi SS, Weng Z, Vreven T, Pierce BG, Borrman TM, Yu J, Ochsenbein F, Guerois R, Vangone A, Rodrigues JP, van Zundert G, Nellen M, Xue L, Karaca E, Melquiond AS, Visscher K, <strong>Kastritis PL<\/strong>, Bonvin AM, Xu X, Qiu L, Yan C, Li J, Ma Z, Cheng J, Zou X, Shen Y, Peterson LX, Kim HR, Roy A, Han X, Esquivel-Rodriguez J, Kihara D, Yu X, Bruce NJ, Fuller JC, Wade RC, Anishchenko I, Kundrotas PJ, Vakser IA, Imai K, Yamada K, Oda T, Nakamura T, Tomii K, Pallara C, Romero-Durana M, Jim\u00e9nez-Garc\u00eda B, Moal IH, F\u00e9rnandez-Recio J, Joung JY, Kim JY, Joo K, Lee J, Kozakov D, Vajda S, Mottarella S, Hall DR, Beglov D, Mamonov A, Xia B, Bohnuud T, Del Carpio CA, Ichiishi E, Marze N, Kuroda D, Roy Burman SS, Gray JJ, Chermak E, Cavallo L, Oliva R, Tovchigrechko A, Wodak SJ.<br \/>\n<em>Proteins<\/em>. 2016 Sep;84 Suppl 1:323-48. doi: 10.1002\/prot.25007. Epub 2016 Jun 1.<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0304383516301719\" target=\"_blank\" rel=\"noopener noreferrer\">New potential peptide therapeutics perturbing CK1\u03b4\/\u03b1-tubulin interaction.<\/a><br \/>\nKr\u00fcger M, Kalbacher H, <strong>Kastritis PL<\/strong>, Bischof J, Barth H, Henne-Bruns D, Vorgias C, Sarno S, Pinna LA, Knippschild U.<br \/>\n<em>Cancer Lett<\/em>. 2016 Jun 1;375(2):375-383. doi: 10.1016\/j.canlet.2016.03.021. Epub 2016 Mar 17.<\/li>\n<li><a href=\"https:\/\/genomebiology.biomedcentral.com\/articles\/10.1186\/s13059-016-0912-5\" target=\"_blank\" rel=\"noopener noreferrer\">Spatiotemporal variation of mammalian protein complex stoichiometries.<\/a><br \/>\nOri A, Iskar M, Buczak K, <strong>Kastritis PL<\/strong>, Parca L, Andr\u00e9s-Pons A, Singer S, Bork P, Beck M.<br \/>\n<em>Genome Biol<\/em>. 2016 Mar 14;17:47. doi: 10.1186\/s13059-016-0912-5.<\/li>\n<li><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0146457\" target=\"_blank\" rel=\"noopener noreferrer\">The Combination of X-Ray Crystallography and Cryo-Electron Microscopy Provides Insight into the Overall Architecture of the Dodecameric Rvb1\/Rvb2 Complex.<\/a><br \/>\nSilva-Martin N, Daud\u00e9n MI, Glatt S, Hoffmann NA, <strong>Kastritis PL<\/strong>, Bork P, Beck M, M\u00fcller CW.<br \/>\n<em>PLoS One<\/em>. 2016 Jan 8;11(1):e0146457. doi: 10.1371\/journal.pone.0146457. eCollection 2016.<\/li>\n<\/ul>\n<p>2015<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.24741\" target=\"_blank\" rel=\"noopener noreferrer\">Non-interacting surface solvation and dynamics in protein-protein interactions.<\/a><br \/>\nVisscher KM, <strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>Proteins<\/em>. 2015 Mar;83(3):445-58. doi: 10.1002\/prot.24741. Epub 2015 Jan 21.<\/li>\n<li><a href=\"https:\/\/www.nature.com\/articles\/nature15381\" target=\"_blank\" rel=\"noopener noreferrer\">In situ structural analysis of the human nuclear pore complex.<\/a><br \/>\nvon Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L,<strong> Kastritis PL<\/strong>, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, Bork P, Antonin W, Glavy JS, Bui KH, Beck M.<br \/>\n<em>Nature<\/em>. 2015 Oct 1;526(7571):140-143. doi: 10.1038\/nature15381. Epub 2015 Sep 23.<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283615004180\" target=\"_blank\" rel=\"noopener noreferrer\">Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.<\/a><br \/>\nVreven T, Moal IH, Vangone A, Pierce BG, <strong>Kastritis PL<\/strong>, Torchala M, Chaleil R, Jim\u00e9nez-Garc\u00eda B, Bates PA, Fernandez-Recio J, Bonvin AM, Weng Z.<br \/>\n<em>J Mol Biol<\/em>. 2015 Sep 25;427(19):3031-41. doi: 10.1016\/j.jmb.2015.07.016. Epub 2015 Jul 29.<\/li>\n<li><a href=\"http:\/\/jcb.rupress.org\/content\/208\/3\/283\" target=\"_blank\" rel=\"noopener noreferrer\">Structural basis for assembly and function of the Nup82 complex in the nuclear pore scaffold.<\/a><br \/>\nGaik M, Flemming D, von Appen A, <strong>Kastritis PL<\/strong>, M\u00fccke N, Fischer J, Stelter P, Ori A, Bui KH, Ba\u00dfler J, Barbar E, Beck M, Hurt E.<br \/>\n<em>J Cell Biol<\/em>. 2015 Feb 2;208(3):283-97. doi: 10.1083\/jcb.201411003.<\/li>\n<\/ul>\n<p>2014<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283614002010\" target=\"_blank\" rel=\"noopener noreferrer\">Proteins feel more than they see: fine-tuning of binding affinity by properties of the non-interacting surface.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Rodrigues JP, Folkers GE, Boelens R, Bonvin AM.<br \/>\n<em>J Mol Biol<\/em>. 2014 Jul 15;426(14):2632-52. doi: 10.1016\/j.jmb.2014.04.017. Epub 2014 Apr 25.<\/li>\n<li><a href=\"https:\/\/academic.oup.com\/nar\/article\/42\/22\/13525\/2411142\" target=\"_blank\" rel=\"noopener noreferrer\">An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum.<\/a><br \/>\nBock T, Chen WH, Ori A, Malik N, Silva-Martin N, Huerta-Cepas J, Powell ST, <strong>Kastritis PL<\/strong>, Smyshlyaev G, Vonkova I, Kirkpatrick J, Doerks T, Nesme L, Ba\u00dfler J, Kos M, Hurt E, Carlomagno T, Gavin AC, Barabas O, M\u00fcller CW, van Noort V, Beck M, Bork P.<br \/>\n<em>Nucleic Acids Res<\/em>. 2014 Dec 16;42(22):13525-33. doi: 10.1093\/nar\/gku1147. Epub 2014 Nov 14.<\/li>\n<li><a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/ci4005332\" target=\"_blank\" rel=\"noopener noreferrer\">HADDOCK(2P2I): a biophysical model for predicting the binding affinity of protein-protein interaction inhibitors.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Rodrigues JP, Bonvin AM.<br \/>\n<em>J Chem Inf Model.<\/em> 2014 Mar 24;54(3):826-36. doi: 10.1021\/ci4005332. Epub 2014 Feb 27.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.24439\" target=\"_blank\" rel=\"noopener noreferrer\">Blind prediction of interfacial water positions in CAPRI.<\/a><br \/>\nLensink MF, Moal IH, Bates PA, <strong>Kastritis PL<\/strong>, Melquiond AS, Karaca E, Schmitz C, van Dijk M, Bonvin AM, Eisenstein M, Jim\u00e9nez-Garc\u00eda B, Grosdidier S, Solernou A, P\u00e9rez-Cano L, Pallara C, Fern\u00e1ndez-Recio J, Xu J, Muthu P, Praneeth Kilambi K, Gray JJ, Grudinin S, Derevyanko G, Mitchell JC, Wieting J, Kanamori E, Tsuchiya Y, Murakami Y, Sarmiento J, Standley DM, Shirota M, Kinoshita K, Nakamura H, Chavent M, Ritchie DW, Park H, Ko J, Lee H, Seok C, Shen Y, Kozakov D, Vajda S, Kundrotas PJ, Vakser IA, Pierce BG, Hwang H, Vreven T, Weng Z, Buch I, Farkash E, Wolfson HJ, Zacharias M, Qin S, Zhou HX, Huang SY, Zou X, Wojdyla JA, Kleanthous C, Wodak SJ.<br \/>\n<em>Proteins<\/em>. 2014 Apr;82(4):620-32. doi: 10.1002\/prot.24439. Epub 2013 Nov 23.<\/li>\n<\/ul>\n<p>2013<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0959440X13001218\" target=\"_blank\" rel=\"noopener noreferrer\">Molecular origins of binding affinity: seeking the Archimedean point.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>Curr Opin Struct Biol<\/em>. 2013 Dec;23(6):868-77. doi: 10.1016\/j.sbi.2013.07.001. Epub 2013 Jul 19. Review.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.24382\" target=\"_blank\" rel=\"noopener noreferrer\">Defining the limits of homology modeling in information-driven protein docking.<\/a><br \/>\nRodrigues JP, Melquiond AS, Karaca E, Trellet M, van Dijk M, van Zundert GC, Schmitz C, de Vries SJ, Bordogna A, Bonati L, <strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>Proteins<\/em>. 2013 Dec;81(12):2119-28. doi: 10.1002\/prot.24382. Epub 2013 Oct 17.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.24356\" target=\"_blank\" rel=\"noopener noreferrer\">Community-wide evaluation of methods for predicting the effect of mutations on protein-protein interactions.<\/a><br \/>\nMoretti R, Fleishman SJ, Agius R, Torchala M, Bates PA, <strong>Kastritis PL<\/strong>, Rodrigues JP, Trellet M, Bonvin AM, Cui M, Rooman M, Gillis D, Dehouck Y, Moal I, Romero-Durana M, Perez-Cano L, Pallara C, Jimenez B, Fernandez-Recio J, Flores S, Pacella M, Praneeth Kilambi K, Gray JJ, Popov P, Grudinin S, Esquivel-Rodr\u00edguez J, Kihara D, Zhao N, Korkin D, Zhu X, Demerdash ON, Mitchell JC, Kanamori E, Tsuchiya Y, Nakamura H, Lee H, Park H, Seok C, Sarmiento J, Liang S, Teraguchi S, Standley DM, Shimoyama H, Terashi G, Takeda-Shitaka M, Iwadate M, Umeyama H, Beglov D, Hall DR, Kozakov D, Vajda S, Pierce BG, Hwang H, Vreven T, Weng Z, Huang Y, Li H, Yang X, Ji X, Liu S, Xiao Y, Zacharias M, Qin S, Zhou HX, Huang SY, Zou X, Velankar S, Janin J, Wodak SJ, Baker D.<br \/>\n<em>Proteins<\/em>. 2013 Nov;81(11):1980-7. doi: 10.1002\/prot.24356. Epub 2013 Aug 23.<\/li>\n<li><a href=\"https:\/\/link.springer.com\/article\/10.1007\/s10858-013-9734-x\" target=\"_blank\" rel=\"noopener noreferrer\">Solvated protein-DNA docking using HADDOCK.<\/a><br \/>\nvan Dijk M, Visscher KM, <strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>J Biomol NMR<\/em>. 2013 May;56(1):51-63. doi: 10.1007\/s10858-013-9734-x. Epub 2013 Apr 30.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.24210\" target=\"_blank\" rel=\"noopener noreferrer\">Solvated protein-protein docking using Kyte-Doolittle-based water preferences.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Visscher KM, van Dijk AD, Bonvin AM.<br \/>\n<em>Proteins<\/em>. 2013 Mar;81(3):510-8. doi: 10.1002\/prot.24210. Epub 2012 Dec 24.<\/li>\n<li><a href=\"https:\/\/link.springer.com\/referenceworkentry\/10.1007%2F978-3-642-16712-6_330\" target=\"_blank\" rel=\"noopener noreferrer\">HADDOCK.<\/a><br \/>\nBonvin AM, van Dijk M, Karaca E, <strong>Kastritis PL<\/strong>, Melquiond ASJ, Schmitz C, de Vries SJ.<br \/>\n<em>Encyclopedia of Biophysics, Springer.<\/em> 2013 943-944. doi:10.1007\/978-3-642-16712-6_330<\/li>\n<\/ul>\n<p>2012<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/royalsocietypublishing.org\/doi\/full\/10.1098\/rsif.2012.0835?url_ver=Z39.88-2003&amp;rfr_id=ori%3Arid%3Acrossref.org&amp;rfr_dat=cr_pub%3Dpubmed&amp;\" target=\"_blank\" rel=\"noopener noreferrer\">On the binding affinity of macromolecular interactions: daring to ask why proteins interact.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>J R Soc Interface<\/em>. 2012 Dec 12;10(79):20120835. doi: 10.1098\/rsif.2012.0835. Print 2013 Feb. Review.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/prot.24078\" target=\"_blank\" rel=\"noopener noreferrer\">Clustering biomolecular complexes by residue contacts similarity.<\/a><br \/>\nRodrigues JP, Trellet M, Schmitz C, <strong>Kastritis PL<\/strong>, Karaca E, Melquiond AS, Bonvin AM.<br \/>\n<em>Proteins<\/em>. 2012 Jul;80(7):1810-7. doi: 10.1002\/prot.24078. Epub 2012 May 8.<\/li>\n<li><a href=\"https:\/\/link.springer.com\/protocol\/10.1007\/978-1-61779-465-0_22\" target=\"_blank\" rel=\"noopener noreferrer\">Explicit treatment of water molecules in data-driven protein-protein docking: the solvated HADDOCKing approach.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, van Dijk AD, Bonvin AM.<br \/>\n<em>Methods Mol Biol<\/em>. 2012;819:355-74. doi: 10.1007\/978-1-61779-465-0_22.<\/li>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/wcms.91\" target=\"_blank\" rel=\"noopener noreferrer\">Next challenges in protein\u2013protein docking: from proteome to interactome and beyond.<\/a><br \/>\nMelquiond AS, Karaca E,&nbsp;<strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>WIRES Comput Mol Sci.<\/em> 2012;2:642-651. doi: 10.1002\/wcms.91<\/li>\n<li><a href=\"https:\/\/www.cabi.org\/cabebooks\/ebook\/20123306555\" target=\"_blank\" rel=\"noopener noreferrer\">Predicting and dissecting high-order molecular complexity by Information-driven Biomolecular Docking<\/a><br \/>\n<strong>Kastritis PL<\/strong> &amp; Bonvin AM.<br \/>\n<em>Antimicrobial Drug Discovery: Emerging Strategies<\/em>. 2012; 22:232246.<\/li>\n<li>\n<div class=\"gs_gray\"><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/abs\/10.1002\/9783527644506.ch32\" target=\"_blank\" rel=\"noopener noreferrer\">Protein-protein docking with HADDOCK.<\/a><\/div>\n<p>Schmitz C, Melquiond ASJ, de Vries SJ, Karaca E, van Dijk M,<strong> Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>NMR of biomolecules: towards mechanistic systems biology<\/em>. 2012;520-535. doi: 10.1002\/9783527644506.ch32<\/li>\n<\/ul>\n<p>2011<\/p>\n<ul>\n<li><strong>*<\/strong><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/full\/10.1002\/pro.580\" target=\"_blank\" rel=\"noopener noreferrer\">A structure-based benchmark for protein-protein binding affinity.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Moal IH, Hwang H, Weng Z, Bates PA, Bonvin AM, Janin J.<br \/>\n<em>Protein Sci<\/em>. 2011 Mar;20(3):482-91. doi: 10.1002\/pro.580. Epub 2011 Feb 16.<\/li>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0022283611010552\" target=\"_blank\" rel=\"noopener noreferrer\">Community-wide assessment of protein-interface modeling suggests improvements to design methodology.<\/a><br \/>\nFleishman SJ, Whitehead TA, Strauch EM, Corn JE, Qin S, Zhou HX, Mitchell JC, Demerdash ON, Takeda-Shitaka M, Terashi G, Moal IH, Li X, Bates PA, Zacharias M, Park H, Ko JS, Lee H, Seok C, Bourquard T, Bernauer J, Poupon A, Az\u00e9 J, Soner S, Ovali SK, Ozbek P, Tal NB, Haliloglu T, Hwang H, Vreven T, Pierce BG, Weng Z, P\u00e9rez-Cano L, Pons C, Fern\u00e1ndez-Recio J, Jiang F, Yang F, Gong X, Cao L, Xu X, Liu B, Wang P, Li C, Wang C, Robert CH, Guharoy M, Liu S, Huang Y, Li L, Guo D, Chen Y, Xiao Y, London N, Itzhaki Z, Schueler-Furman O, Inbar Y, Potapov V, Cohen M, Schreiber G, Tsuchiya Y, Kanamori E, Standley DM, Nakamura H, Kinoshita K, Driggers CM, Hall RG, Morgan JL, Hsu VL, Zhan J, Yang Y, Zhou Y, <strong>Kastritis PL<\/strong>, Bonvin AM, Zhang W, Camacho CJ, Kilambi KP, Sircar A, Gray JJ, Ohue M, Uchikoga N, Matsuzaki Y, Ishida T, Akiyama Y, Khashan R, Bush S, Fouches D, Tropsha A, Esquivel-Rodr\u00edguez J, Kihara D, Stranges PB, Jacak R, Kuhlman B, Huang SY, Zou X, Wodak SJ, Janin J, Baker D.<br \/>\n<em>J Mol Biol<\/em>. 2011 Nov 25;414(2):289-302. doi: 10.1016\/j.jmb.2011.09.031. Epub 2011 Sep 29.<\/li>\n<li><a href=\"https:\/\/journals.plos.org\/plosone\/article?id=10.1371\/journal.pone.0018127\" target=\"_blank\" rel=\"noopener noreferrer\">Antimicrobial and efflux pump inhibitory activity of caffeoylquinic acids from Artemisia absinthium against gram-positive pathogenic bacteria.<\/a><br \/>\nFiamegos YC, <strong>Kastritis PL<\/strong>, Exarchou V, Han H, Bonvin AM, Vervoort J, Lewis K, Hamblin MR, Tegos GP.<br \/>\n<em>PLoS One<\/em>. 2011 Apr 4;6(4):e18127. doi: 10.1371\/journal.pone.0018127.<\/li>\n<\/ul>\n<p>2010<\/p>\n<ul>\n<li><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/prot.22814\" target=\"_blank\" rel=\"noopener noreferrer\">Strengths and weaknesses of data-driven docking in critical assessment of prediction of interactions.<\/a><br \/>\nde Vries SJ, Melquiond AS, <strong>Kastritis PL<\/strong>, Karaca E, Bordogna A, van Dijk M, Rodrigues JP, Bonvin AM.<br \/>\n<em>Proteins<\/em>. 2010 Nov 15;78(15):3242-9. doi: 10.1002\/prot.22814.<\/li>\n<li><a href=\"https:\/\/pubs.acs.org\/doi\/abs\/10.1021\/pr9009854\" target=\"_blank\" rel=\"noopener noreferrer\">Are scoring functions in protein-protein docking ready to predict interactomes? Clues from a novel binding affinity benchmark.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>J Proteome Res<\/em>. 2010 May 7;9(5):2216-25. doi: 10.1021\/pr9009854. Erratum in: <em>J Proteome Res<\/em>. 2011 Feb 4;10(2):921-2.<\/li>\n<li><a href=\"https:\/\/www.mcponline.org\/content\/9\/8\/1784\" target=\"_blank\" rel=\"noopener noreferrer\">Building macromolecular assemblies by information-driven docking: introducing the HADDOCK multibody docking server.<\/a><br \/>\nKaraca E, Melquiond AS, de Vries SJ, <strong>Kastritis PL<\/strong>, Bonvin AM.<br \/>\n<em>Mol Cell Proteomics<\/em>. 2010 Aug;9(8):1784-94. doi: 10.1074\/mcp.M000051-MCP201. Epub 2010 Mar 19.<\/li>\n<\/ul>\n<p>2007<\/p>\n<ul>\n<li><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S014181300700147X\" target=\"_blank\" rel=\"noopener noreferrer\">Haloadaptation: insights from comparative modeling studies of halophilic archaeal DHFRs.<\/a><br \/>\n<strong>Kastritis PL<\/strong>, Papandreou NC, Hamodrakas SJ.<br \/>\n<em>Int J Biol Macromol<\/em>. 2007 Oct 1;41(4):447-53. Epub 2007 Jun 19.<\/li>\n<\/ul>\n<p><a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02.png\"><img loading=\"lazy\" class=\"aligncenter wp-image-374 size-thumbnail\" src=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-150x150.png\" alt=\"\" width=\"150\" height=\"150\" srcset=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-150x150.png 150w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-300x300.png 300w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-1024x1024.png 1024w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-768x768.png 768w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-1536x1536.png 1536w, https:\/\/blogs.urz.uni-halle.de\/kastritislab\/files\/2020\/04\/Lab-logo02-2048x2048.png 2048w\" sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Publications with an asterisk (*) are considered highly relevant to our lab projects. Publications with 2 asterisks (**) are relevant for researching SARS-CoV-2. Lab members are shown underlined 2026 *Accessing new dimensions in high-resolution materials exploration by cryo-electron microscopy. Koralli <a class=\"more-link\" href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/publications\/\">Continue reading <span class=\"screen-reader-text\">  Publications<\/span><span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":4167,"featured_media":0,"parent":0,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0},"_links":{"self":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages\/25"}],"collection":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/users\/4167"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":9,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":790,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages\/25\/revisions\/790"}],"wp:attachment":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}