{"id":411,"date":"2020-06-10T18:26:55","date_gmt":"2020-06-10T16:26:55","guid":{"rendered":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/?page_id=411"},"modified":"2021-04-22T12:40:26","modified_gmt":"2021-04-22T10:40:26","slug":"researching-sars-cov-2","status":"publish","type":"page","link":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/researching-sars-cov-2\/","title":{"rendered":"Researching SARS-CoV-2"},"content":{"rendered":"\n<p class=\"has-background\" style=\"background-color:#fff1f1\">Our laboratory is focusing its efforts to model, dissect and understand the recognition of the SARS-CoV-2 virus by the epithelial cells. In particular, we seek to answer how genetic variation in the epithelial receptor, ACE2, and the virus can cross-talk in order to finely modulate infection. <br>Please check the <a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/publications\/\">Publication List<\/a> or announcement sections for work related to the research of this new virus that has so greatly affected and altered our lives.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/2021\/02\/jaydeep-belapure-a-previous-thermo-fisher-engineer-joins-our-lab-for-amazing-machine-learning-in-cryoem-images\/\" data-type=\"post\" data-id=\"477\">announcement #4<\/a> <strong>Dr. Jaydeep Belapure joins the lab to perform computational biology for understanding S protein-ACE2 receptor recognition!<\/strong><br><a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/2020\/06\/insights-into-sars-cov-2-cross-species-transmission-together-with-our-collaborators-from-the-u-s-canada-and-spain\/\">announcement #3<\/a> (on receiving a BMBF grant for studying COVID-19): <strong>Two new post-docs will be joining my laboratory to fight SARS-Cov-2!<\/strong><br><a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/2020\/06\/insights-into-sars-cov-2-cross-species-transmission-together-with-our-collaborators-from-the-u-s-canada-and-spain\/\">announcement #2<\/a> (on ACE2 receptor variants): <strong>Models provided for the community for cryoEM and crystal complexes of SARS-CoV-2 S-protein and ACE2 receptor variants!<\/strong> Find the models <a rel=\"noreferrer noopener\" href=\"https:\/\/kastritislab.github.io\/human-ace2-variants\/\" target=\"_blank\">here, in our Lab GitHub!<\/a><br><a href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/2020\/06\/insights-into-sars-cov-2-cross-species-transmission-together-with-our-collaborators-from-the-u-s-canada-and-spain\/\">announcement #1<\/a> (on cross-species transmission): <strong>Which reasons are behind the fact that some species get infected by SARS-CoV-2 while others don&#8217;t?<\/strong><br><br><br><br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Our laboratory is focusing its efforts to model, dissect and understand the recognition of the SARS-CoV-2 virus by the epithelial cells. In particular, we seek to answer how genetic variation in the epithelial receptor, ACE2, and the virus can cross-talk <a class=\"more-link\" href=\"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/researching-sars-cov-2\/\">Continue reading <span class=\"screen-reader-text\">  Researching SARS-CoV-2<\/span><span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":4167,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"ngg_post_thumbnail":0},"_links":{"self":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages\/411"}],"collection":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/users\/4167"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/comments?post=411"}],"version-history":[{"count":8,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages\/411\/revisions"}],"predecessor-version":[{"id":499,"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/pages\/411\/revisions\/499"}],"wp:attachment":[{"href":"https:\/\/blogs.urz.uni-halle.de\/kastritislab\/wp-json\/wp\/v2\/media?parent=411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}