We do have a waters Synapt G2-S, which also features ion mobility mass spectrometry… Ion-mobility spectrometry–mass spectrometry

Hyphenated techniques combine chromatographic and spectral methods to exploit the advantages of both techniques. High-performance liquid chromatography (HPLC; formerly referred as high-pressure liquid chromatography or hewlett-packard liquid chromatography) separates components out of a mixtureusing pressurized liquid sovents (containing the sample mixture) through a column filled with solid adsorbent. Because each component will slightly differently interact with mobile […]

Some basic reviews as selected by Sacha: Mass spectrometry and protein analysis. Domon B, Aebersold R. Science. 2006 Apr 14;312(5771):212-7 Science-2006-Domon-212-7 Options and considerations when selecting a quantitative proteomics strategy. Domon B, Aebersold R. Nat Biotechnol. 2010 Jul;28(7):710-21. doi: 10.1038/nbt.1661 nbt.1661 Phosphoproteomics–more than meets the eye. Loroch S, Dickhut C, Zahedi RP, Sickmann A. Electrophoresis. […]