Cell Physiology Department

Publications (Prof. K. Kühn)


Saleh O, Dwiani S, Rott J, Kühn K. Nascent Transcript Sequencing for the Mapping of Promoters in Arabidopsis thaliana Mitochondria. Methods Mol Biol. in press

Kim M, Schulz V, Brings L, Schoeller T, Kühn K, Vierling E. mTERF18 and ATAD3 are required for mitochondrial nucleoid structure and their disruption confers heat tolerance in Arabidopsis thaliana. New Phytol. in press


Fuchs P, Rugen N, Carrie C, Elsässer M, Finkemeier I, Giese J, Hildebrandt TM, Kühn K, Maurino VG, Ruberti C, Schallenberg-Rüdinger M, Steinbeck J, Braun HP, Eubel H, Meyer EH, Müller-Schüssele SJ, Schwarzländer M. (2019). Single organelle function and organization as estimated from Arabidopsis mitochondrial proteomics. Plant J. 101(2):420-441.


Meyer, E.H., Lehmann, C., Boivin, S., Brings, L., De Cauwer, I., Bock, R., Kühn, K., and Touzet, P. (2018). CMS-G from Beta vulgaris ssp. maritima is maintained in natural populations despite containing an atypical cytochrome c oxidase. Biochem J. 475, 759-773.


Teubner, M., Fuss, J., Kühn, K., Krause, K., and Schmitz-Linneweber, C. (2017). The RNA recognition motif protein CP33A is a global ligand of chloroplast mRNAs and is essential for plastid biogenesis and plant development. Plant J. 89, 472-485.


Romani, I., Manavski, N., Morosetti, A., Tadini, L., Maier, S., Kühn, K., Ruwe, H., Schmitz-Linneweber, C., Wanner, G., Leister, D., and Kleine, T. (2015). A Member of the Arabidopsis Mitochondrial Transcription Termination Factor Family Is Required for Maturation of Chloroplast Transfer RNAIle(GAU). Plant Physiol 169, 627-646.

Kühn, K., Obata, T., Feher, K., Bock, R., Fernie, A.R., and Meyer, E.H. (2015). Complete mitochondrial complex I deficiency induces an upregulation of respiratory fluxes that is abolished by traces of functional complex I. Plant Physiol 168, 1537-1549.

Gualberto, J.M., Le Ret, M., Beator B., and Kühn, K. (2015). The RAD52-like protein ODB1 is required for the efficient excision of two mitochondrial introns spliced via first-step hydrolysis. Nucleic Acids Res 43, 6500-6510.

Binder, S., and Kühn, K. (2015). Determining mitochondrial transcript termini for the study of transcription start sites and transcript 5′ end maturation. Methods Mol Biol 1305, 13-30.

Kühn, K. (2015). Mitochondrial run-on transcription assay using biotin labeling. Methods Mol Biol 1305, 31-44.

Kühn, K., Yin, G., Duncan, O., Law, S.R., Kubiszewski-Jakubiak, S., Kaur, P., Meyer, E., Wang, Y., Colas des Francs-Small, C., Giraud, E., Narsai, R., and Whelan, J. (2015). Decreasing electron flux through the cytochrome and/or alternative respiratory pathways triggers common and distinct cellular responses dependent on growth conditions. Plant Physiol 167, 228-250.


Gualberto, J.M., and Kühn, K. (2014). DNA-binding proteins in plant mitochondria: Implications for transcription. Mitochondrion 19 Pt B, 323-328.

Braun, H.P., Binder, S., Brennicke, A., Eubel, H., Fernie, A.R., Finkemeier, I., Klodmann, J., König, A.C., Kühn, K., Meyer, E., Obata, T., Schwarzländer, M., Takenaka, M., and Zehrmann, A. (2014). The life of plant mitochondrial complex I. Mitochondrion 19 Pt B, 295-313.


Kühn, K., and Gualberto, J.M. (2012). Recombination in the stability, repair and evolution of the mitochondrial genome. In Mitochondrial Genome Evolution, L. Maréchal-Drouard, ed (London: Academic Press Ltd-Elsevier Science Ltd), pp. 215-252.

Janicka, S., Kühn, K., Le Ret, M., Bonnard, G., Imbault, P., Augustyniak, H., and Gualberto, J.M. (2012). A RAD52-like single-stranded DNA binding protein affects mitochondrial DNA repair by recombination. Plant J 72, 423-435.

Miller-Messmer, M., Kühn, K., Bichara, M., Le Ret, M., Imbault, P., and Gualberto, J. (2012). RECA-dependent DNA repair results in increased heteroplasmy of the Arabidopsis mitochondrial genome. Plant Physiol 159, 211-226.

Zhu, Q., Dugardeyn, J., Zhang, C., Takenaka, M., Kühn, K., Craddock, C., Smalle, J., Karampelias, M., Denecke, J., Peters, J., Gerats, T., Brennicke, A., Eastmond, P., Meyer, E.H., and Van Der Straeten, D. (2012). SLO2, a mitochondrial pentatricopeptide repeat protein affecting several RNA editing sites, is required for energy metabolism. Plant J 71, 836-849.

2011 and earlier

Kühn, K., Carrie, C., Giraud, E., Wang, Y., Meyer, E.H., Narsai, R., Colas des Francs-Small, C., Zhang, B., Murcha, M.W., and Whelan, J. (2011). The RCC1 family protein RUG3 is required for splicing of nad2 and complex I biogenesis in mitochondria of Arabidopsis thaliana. Plant J 67, 1067-1080.

Richter, U., Kühn, K., Okada, S., Brennicke, A., Weihe, A., and Börner, T. (2010). A mitochondrial rRNA dimethyladenosine methyltransferase in Arabidopsis. Plant J 61, 558-569.

Kühn, K., Richter, U., Meyer, E.H., Delannoy, E., Falcon de Longevialle, A., O’Toole, N., Börner, T., Millar, A.H., Small, I.D., and Whelan, J. (2009). Phage-type RNA polymerase RPOTmp performs gene-specific transcription in mitochondria of Arabidopsis thaliana. Plant Cell 21, 2762-2779.

Carrie, C., Kühn, K., Murcha, M.W., Duncan, O., Small, I.D., O’Toole, N., and Whelan, J. (2009). Approaches to defining dual-targeted proteins in Arabidopsis. Plant J 57, 1128-1139.

Carrie, C., Murcha, M.W., Kuehn, K., Duncan, O., Barthet, M., Smith, P.M., Eubel, H., Meyer, E., Day, D.A., Millar, A.H., and Whelan, J. (2008). Type II NAD(P)H dehydrogenases are targeted to mitochondria and chloroplasts or peroxisomes in Arabidopsis thaliana. FEBS Lett 582, 3073-3079.

Kühn, K., Bohne, A.V., Liere, K., Weihe, A., and Börner, T. (2007). Arabidopsis phage-type RNA polymerases: accurate in vitro transcription of organellar genes. Plant Cell 19, 959-971.

Holec, S., Lange, H., Kühn, K., Alioua, M., Börner, T., and Gagliardi, D. (2006). Relaxed transcription in Arabidopsis mitochondria is counterbalanced by RNA stability control mediated by polyadenylation and polynucleotide phosphorylase. Mol Cell Biol 26, 2869-2876.

Kühn, K., Weihe, A., and Börner, T. (2005). Multiple promoters are a common feature of mitochondrial genes in Arabidopsis. Nucleic Acids Res 33, 337-346.

Morais, F., Kühn, K., Stewart, D.H., Barber, J., Brudvig, G.W., and Nixon, P.J. (2001). Photosynthetic water oxidation in cytochrome b(559) mutants containing a disrupted heme-binding pocket. J Biol Chem 276, 31986-31993.