I am pleased to inform our fans 🙂 that the laboratory received substantial funding for 3 years to hire 2 post-doctoral researchers and work in the fields of (a) cryoEM and (b) computational biology for COVID-19. We applied together with Prof. Stubbs, crystallographer, and Prof. Bacia, physical chemist, and acquired in total funding for consumables, 5 post-doctoral researchers, a coordinator and some associated infrastructure for “CORONAmem: Molekulare Determinanten der differentiellen Wirtsanfälligkeit gegenüber SARS‐CoV‐2 am Eintrittspunkt”.
We strengthened this grant with our work previously performed with our Ph.D. student Marija and our collaborator from Stanford, Dr. João Rodrigues!
Structural models of human ACE2 variants with SARS-CoV-2 Spike protein for structure-based drug design.
Sorokina M, M C Teixeira J, Barrera-Vilarmau S, Paschke R, Papasotiriou I, Rodrigues JPGLM, Kastritis PL*
Scientific Data. 2020 Sep 16;7(1):309. doi: 10.1038/s41597-020-00652-6.
Insights on cross-species transmission of SARS-CoV-2 from structural modeling.
Rodrigues PGLM J*, Barrera-Vilarmau S, Texeira MC J, Seckel E, Kastritis PL, Levitt M.
PLoS computational biology 2020 16 (12), e1008449
[preprint was @BioRxiv 2020 2020.06.05.136861. doi: 10.1101/2020.06.05.136861]