Cryo-EM, Computation and Metabolons
We welcome 2022 with our latest publication on Structure, on how the latest advances in AI-driven protein model prediction can help us in the interpretation of complex cryo-EM data from native cell extracts! We are very excited about the impact Continue reading Cryo-EM combined with AI to advance our understanding of native cell extracts!
I am feeling very proud and honored to have worked together with my team to publish this seminal work of us in Cell Reports. This work described for the first time the endogenous, full metabolon of pyruvate oxidation with cryoEM Continue reading The seminal lab paper is out! Visualizing metabolons from native cell extracts at unprecedented resolution!
Secured €9.2 million in funding from the European (ERDF/EFRE) and State sources to upgrade my cryo-EM infrastructure at The Martin Luther University of Halle-Wittenberg – We will accelerate structural biology, materials, and green energy research!I deeply thank my lab members, Continue reading Incredible news to kick off 2025! 🥳
After a year of leading the two laboratories, I am pleased to say that knowledge transfer to NHRF is efficiently happening, while in Halle the laboratory produced high-level teaching and research at extremely high level. We also had a lab Continue reading Really happy with both laboratories – MLU Halle & NHRF Athens celebrating 1 year!
After a successful and fast installation today, we are pleased to communicate that we now have -besides 26 GPUs and 1.3 PB of space- an additional 0.5 PB of storage in our rack! Christian has done an amazing job. As Continue reading Additional storage of 0.5 PB is up and running!
In a collaborative effort with the Sinz lab, our Post-doc Christian led a project on the utilization of AI-derived protein modeling based on mass spectrometry data, in order to interpret unknown cryo-EM maps from within native cell extracts! This type Continue reading AlphaFold2 and Proteomics data help interpret native cell extracts
Panos was invited as a keynote speaker at the Grenoble research consortium in integrated structural & cell biology and their annual event #48hofGRAL, where he presented our lab’s research on cell extracts and the pipelines we use to integrate data Continue reading Panos at the 48 hours of Grenoble Structural Biology