Author Archives: Panagiotis Kastritis

The seminal lab paper is out! Visualizing metabolons from native cell extracts at unprecedented resolution!

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I am feeling very proud and honored to have worked together with my team to publish this seminal work of us in Cell Reports. This work described for the first time the endogenous, full metabolon of pyruvate oxidation with cryoEM Continue reading The seminal lab paper is out! Visualizing metabolons from native cell extracts at unprecedented resolution!→

Jaydeep Belapure, a previous Thermo Fisher Senior Scientist joins our lab for amazing machine learning in cryoEM images!

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Jaydeep Belapure, Ph.D. in physics from TUM joins our lab as a postdoc in the CORONAmem grant that we acquired recently. Another addition in the multicultural environment of the lab is welcome, raising the different nationalities to 6!We are going Continue reading Jaydeep Belapure, a previous Thermo Fisher Senior Scientist joins our lab for amazing machine learning in cryoEM images!→

Our point-of-view for the function of disorder in large complexes is out!

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We have authored a manuscript where we bring to attention large metabolons which catalyze essential reactions, producing, converting, or accepting small molecules with critical signaling functions. These metabolons include a significant amount of disorder, consistently in important regions for enzyme Continue reading Our point-of-view for the function of disorder in large complexes is out!→