Kastritis Laboratory for Biomolecular Research
Cryo-EM, Computation and Metabolons
In a collaborative effort with the Sinz lab, our Post-doc Christian led a project on the utilization of AI-derived protein modeling based on mass spectrometry data, in order to interpret unknown cryo-EM maps from within native cell extracts! This type Continue reading AlphaFold2 and Proteomics data help interpret native cell extracts
Panos and Fotis visited the Cryo-EM facility of Thermo Fisher Scientific in Eindhoven, NL to get a tour of the facility, do some “shopping” and collect tomography data! Thermo application scientists gave them a presentation on the functionalities and efficacy Continue reading A visit at the Thermo Fisher Scientific Headquarters for Cryo-EM
Our work on how cryo-EM and AI can be combined to structurally characterize protein community members from native cell extracts is featured on the cover of the April Issue of Structure! We want to thank again our lab members and Continue reading On the cover of Structure
We welcome 2022 with our latest publication on Structure, on how the latest advances in AI-driven protein model prediction can help us in the interpretation of complex cryo-EM data from native cell extracts! We are very excited about the impact Continue reading Cryo-EM combined with AI to advance our understanding of native cell extracts!
Our PostDoc Dmitry actively shows that the Kastritis lab is not just working on our model organism C. thermophilum! Dmitry is very interested in the Photosynthesis machinery and through his collaborations with the Bruce Lab @ UTK, and his former Continue reading 44 subunits, 448 cofactors, 1 high-resolution Photosystem I map, tons of insights into Photosynthesis!