Structural insights into a metabolon-embedded transacetylase reaction powered by Cryo-EM!

Our latest work on the structure and function of the native Pyruvate Dehydrogenase Complex Core is now online, showing once again the power of our lab’s integrative approach! Cryo-EM, macromolecular docking and molecular dynamics simulations are combined to provide insights Continue reading Structural insights into a metabolon-embedded transacetylase reaction powered by Cryo-EM!

Protocol paper on the usage of restraints with HADDOCK

We are very happy to have communicated in the prestigious journal Nature Protocols along with collaborators and other developers of HADDOCK, a short descriptions on how to include cross-linking data in the modelling of protein-protein complexes. For more information, visit Continue reading Protocol paper on the usage of restraints with HADDOCK