cell extracts – Kastritis Laboratory for Biomolecular Research

Structural insights into a metabolon-embedded transacetylase reaction powered by Cryo-EM!

Posted on 26/11/2021 by Ioannis Skalidis — No Comments ↓

Our latest work on the structure and function of the native Pyruvate Dehydrogenase Complex Core is now online, showing once again the power of our lab’s integrative approach! Cryo-EM, macromolecular docking and molecular dynamics simulations are combined to provide insights Continue reading Structural insights into a metabolon-embedded transacetylase reaction powered by Cryo-EM!→

The Kastritis Lab in “Bringing Molecular Structure to Life: 50 years of PDB” Conference!

Posted on 24/10/2021 by Ioannis Skalidis — No Comments ↓

The conference for the anniversary of 50 years from the creation of the Protein Data Bank took place from the 20th to the 22nd of October, organized by EMBL, with online participation. Of course our lab could not miss the Continue reading The Kastritis Lab in “Bringing Molecular Structure to Life: 50 years of PDB” Conference!→

Our seminal paper on structural analysis of metabolons from native cell extracts rides the news!

Posted on 22/04/2021 by Panagiotis Kastritis — No Comments ↓

It is very nice that our paper got significant interest across media and newspapers, in the regional, national, and international levels! Some articles describing the work from my lab are listed below and can be found at >10 news agencies! Continue reading Our seminal paper on structural analysis of metabolons from native cell extracts rides the news!→

Our perspective on how to implement machine learning tools together with traditional computational analysis for native cell extracts is out!

Posted on 18/04/2021 by Panagiotis Kastritis — No Comments ↓

With our new post-doc Jaydeep, and Staff Scientist, Fotis, we have published our perspective on experimental and computational analysis of complex mixtures, and in particular our favorite ones, native cell extracts!A lot of work awaits 🙂 Read all about it Continue reading Our perspective on how to implement machine learning tools together with traditional computational analysis for native cell extracts is out!→

The cover for Biol Chem – Structural Biology of Native Cell Extracts

Posted on 14/06/2019 by Panagiotis Kastritis — No Comments ↓

We are very proud for our cover for Biol Chem, July issue – it is currently online, and advertised on the main page of the journal. A high-resolution pdf file with explanation of our cover can be found on the Continue reading The cover for Biol Chem – Structural Biology of Native Cell Extracts→