Organizing an EMBO workshop on the recent advances in structural biology of membrane proteins (and winning another poster prize in the process)!

It turns out that, as Panos found out, organizing an EMBO workshop is hard, but highly rewarding work! Along with Sandro Keller (who is also a close collaborator of our group), Christian Löw and Christina Paulino, our Group Leader Panos Continue reading Organizing an EMBO workshop on the recent advances in structural biology of membrane proteins (and winning another poster prize in the process)!

Structural insights into a metabolon-embedded transacetylase reaction powered by Cryo-EM!

Our latest work on the structure and function of the native Pyruvate Dehydrogenase Complex Core is now online, showing once again the power of our lab’s integrative approach! Cryo-EM, macromolecular docking and molecular dynamics simulations are combined to provide insights Continue reading Structural insights into a metabolon-embedded transacetylase reaction powered by Cryo-EM!

The Kastritis Lab in “Bringing Molecular Structure to Life: 50 years of PDB” Conference!

The conference for the anniversary of 50 years from the creation of the Protein Data Bank took place from the 20th to the 22nd of October, organized by EMBL, with online participation. Of course our lab could not miss the Continue reading The Kastritis Lab in “Bringing Molecular Structure to Life: 50 years of PDB” Conference!

Our seminal paper on structural analysis of metabolons from native cell extracts rides the news!

It is very nice that our paper got significant interest across media and newspapers, in the regional, national, and international levels! Some articles describing the work from my lab are listed below and can be found at >10 news agencies! Continue reading Our seminal paper on structural analysis of metabolons from native cell extracts rides the news!

The seminal lab paper is out! Visualizing metabolons from native cell extracts at unprecedented resolution!

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I am feeling very proud and honored to have worked together with my team to publish this seminal work of us in Cell Reports. This work described for the first time the endogenous, full metabolon of pyruvate oxidation with cryoEM Continue reading The seminal lab paper is out! Visualizing metabolons from native cell extracts at unprecedented resolution!