Kastritis Laboratory for Biomolecular Research
Cryo-EM, Computation and Metabolons
Nature webcasts hosted our Group Leader, Panos, and his talk on how cryo-EM and AI are perfectly suited together in order to investigate native cell extracts! You can find more information about the webcast here. We thank GenScript for their Continue reading Nature webcast – Cryo-EM and artificial intelligence: A marriage made in cell extracts
It is very nice that our paper got significant interest across media and newspapers, in the regional, national, and international levels! Some articles describing the work from my lab are listed below and can be found at >10 news agencies! Continue reading Our seminal paper on structural analysis of metabolons from native cell extracts rides the news!
We are happy to inform you that we collaborated with the MPI in Magdeburg, a work led by Dr.-Ing. Ivan Ivanov, Prof. Dr.-Ing. Kai Sundmacher, and Dr. Rumiana Dimova. We have acquired cryo-EM data for a designed respiratory chain. We Continue reading A respiratory unit visualized by cryo-EM! Our collaboration is published in PNAS
Our paper is available as a pre-print in Biorxiv (https://www.biorxiv.org/content/10.1101/738724v1). In this work, we have determined the atomic structure of mouse apoferritin using the Glacios microscope. Its difference comparedd to other 200 keV microscope is its compact design, allowing the Continue reading Our paper on the 2.7 Å structure of apoferritin with the Glacios and the Falcon 3EC is available as a preprint!
We have successfully vitrified apoferritin in own Vitrobot Mark 4. Loading the microscope and starting EPU yesterday evening ended up with an acquisition of ~300 high-resolution images from a single gridsquare! First of all, we are able to demonstrate the Continue reading Vitrified apoferritin in Halle – first overnight acquisition is complete!