Dr. Jbeily, Mark – Physical chemistry (Kreßler, MLU)

Title of thesis: Fluorophilicity in Biologically Relevant Systems Studied with Fluorinated Rhodamines

Date of defence: April 21, 2017

Research topic: 
Amphiphilic block copolymers synthesis

Methods:

  • Atom Transfer Radical Polymerization (ATRP)
  • Reversible Addition–Fragmentation Chain Transfer (RAFT)
  • Gel Permeation Chromatography (GPC)
  • Synthetic fluorophylic dyes

Successful defence of Mark Jbeily (group of J. Kreßler)

Congratulations to Mark. He defended his thesis successfully and completed the additional training program of our integrated research training group.

Title: Fluorophilicity in Biologically Relevant Systems Studied with Fluorinated Rhodamines

Date: 21.04.2017 at 1.00pm
Location: SR 5.09 , Von-Seckendorff-Platz 1, 06120 Halle

Official announcement

Talk by F. Hoffmann at MLU (April 4, 2017)

Competition between Electrostatic and Hydrophobic Forces in the Central Core Region of Amyloid β Fibrils

Amyloidogenic peptides aggregated to large molecular assemblies are a hallmark of several diseases including Parkinson’s, Huntington’s, and Alzheimer’s disease as well as type II diabetes. Although each of these diseases gives rise to a very distinctive clinical picture, amyloid fibrils share the cross-β structure as a common structural motif. Within this motif, the peptide strands are linked via lateral β-sheet-turn-β-sheet structures that result in fiber-like aggregates with diameters of a few nanometers and lengths up to several micrometers.

The central question that will be addressed is how electrostatic and hydrophobic interactions compete within the central core region of Aβ(1-40) fibrils. Continue reading “Talk by F. Hoffmann at MLU (April 4, 2017)”

iRTG Program SoSe 2017 – Overview

Doctoral students seminars

April 4th at MLU (VDP3, SR 1.09):

Felix Hoffmann on “Competition between Electrostatic and Hydrophobic Forces in the Central Core Region of Amyloid β Fibrils” (abstract)

May 16th at MLU (VDP3, SR 1.09):

Martha Schulz on “Effects of molecular dynamics on morphology and properties of αc-relaxation”

June 13th, at UL (Linnéstr. 5, SR 225):

Torsten John on “Amyloid peptide aggregation near gold interfaces and membranes”

July 18th at MLU (VDP3, SR 1.09):

Mareen Schäfer on “NMR investigations of dynamics in the different phases of semicrystalline polymers”

August at UL:

Tobias Thalheim on “Applying principal components analysis to single DNA molecules in a thermophoretic trap”

September 5th at MLU (VDP3, SR 1.09):

Martin Himmelreich on “The Coupled Folding and Binding Reaction of pKID/KIX”

 Advanced Training Modules

Workshops

Soft skill seminars

Supplementary Study

Career workshop: How to write a persuasive job application – how to convince it in the job interview (June 19-20, 2017)

Scientists make a lot of mistakes as soon as they start to apply outside science. This workshop will help you to write a convincing application and to be successful in the job interview.

Continue reading “Career workshop: How to write a persuasive job application – how to convince it in the job interview (June 19-20, 2017)”

NMR spectroscopy for biomolecular and materials characterization (September 6/7, 2017)

Aims

This module addresses doctoral students in chemistry, physics, biophysics, and related fields without much prior knowledge in NMR spectroscopy. It introduces the basic theoretical and technical concepts necessary for an understanding of data/spectrum acquisition in pulsed NMR and the information content, and focuses on a few specific experimental techniques to study dynamics in polymer and biopolymer systems.

Contents

Each day of the two-day program starts with a series of lectures in the morning, followed by hands-on experiments on low-field NMR spectrometers, and demonstrations on high-field spectrometers, during the afternoon. Continue reading “NMR spectroscopy for biomolecular and materials characterization (September 6/7, 2017)”